Protein Alignment CYP4F8 and Cyp9f2

DIOPT Version :9

• Sequence 1: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 467
• Identity: 100/467 - (21%)
• Similarity: 190/467 - (40%)
• Gaps: 80/467 - (17%)

Human    97 PIINLCHPDIVRSV-INTSDAITDKDIVFYKT-------LKPWLGDGLLLSVGDKWRHHRRLLTP 153
            |::.:..||:::.: |...|...:...||..:       :....|..|......:|:..|..|:|
  Fly    79 PLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSP 143

Human   154 AFHFNILKPYIKIFSKSANIMHAKWQRLAMEGSTC------------LDVFEHISLMTLDSLQKC 206
            ||..:.::...::.:           ::|.|...|            ||:.::.:..|.|.:...
  Fly   144 AFTGSKMRQMFQLMN-----------QVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIAST 197

Human   207 IFSFDSNC-QEKPSEYITAIMELSALVVKRNNQF-----------------FRYKDFLYF--LTP 251
            .|....|. :::.:.:.....:|:.....::.:|                 |..|...||  |..
  Fly   198 AFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVRLVL 262

Human   252 CGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDE 316
            ...::.:...:|......::.|.|..:.::        |.|:..:              :|.||.
  Fly   263 DAMKYRQEHNIVRPDMINMLMEARGIIQTE--------KTKASAV--------------REWSDR 305

Human   317 DIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFL 381
            ||.|:...|.|.|.:|:|..:.:..:.|..:.:.|:|..:|||::.:|.|.||:.::.:..:.:|
  Fly   306 DIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYL 370

Human   382 TMCLKESLRLHPPIPTFARGCTQDVV--LPDSRV-IPKGNVCNINIFAIHHNPSVWPDPEVYDPF 443
            ...:.|.||..|......|.|.:|:.  :...:| :.||:|..:.....|.:|..:.:|..:||.
  Fly   371 DQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPE 435

Human   444 RFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHRE--PRR--TPEI 504
            ||..||.:...|..:.||..|.|||||.:||:.|.|.|:...|..:|..|..:.  |..  |...
  Fly   436 RFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGF 500

Human   505 VLRAEDGLWLRV 516
            .|..:.|.|:::
  Fly   501 QLSPKGGFWIKL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	97/453 (21%)
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	99/463 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810