Protein Alignment CYP4F8 and Cyp9b2

DIOPT Version :9

• Sequence 1: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 126/540 - (23%)
• Similarity: 221/540 - (40%)
• Gaps: 85/540 - (15%)

Human    20 LLLLVVGASWLLARILAWTYAFYHNGRRLRCF---PQPRKQNWFLGHLGLVTPTEEGL-RVLTQL 80
            |.|:|:|  :|   |..|:.|.:......:.:   |.|     |:|::......:... |.||:.
  Fly     8 LALVVIG--YL---IYKWSTATFKTFEERKLYFEKPYP-----FVGNMAAAALQKSSFQRQLTEF 62

Human    81 V-ATYPQGFVRWLGPITPIINLCHPDIVRSVI--------NTSDAITDKDIVFYKTLKPWLGDGL 136
            . .|.....|.:....||:|.|..|::::.|.        |....||..|.:|        .|.|
  Fly    63 YERTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLF--------NDML 119

Human   137 LLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKS--ANIMHAKWQRLAMEGSTCLDVFEHI--SL 197
            .:....:|:|.|..|||.|....::....:.::|  ..:.|.......:.|....:|...:  :.
  Fly   120 SVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNK 184

Human   198 MTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRL 262
            ::.|.:....|....|..:.|......|.:  :||..|..|||::  .|..|.|  :.|......
  Fly   185 LSNDIIATTAFGLKVNSYDNPKNEFYEIGQ--SLVFSRGLQFFKF--MLSTLVP--KLFSLLKLT 243

Human   263 VHDFTDAVIQERRRTLTSQGVDDF-------LQAKAKSKTL--DFIDVLLLSEDKNGKELSDEDI 318
            :.|              |..||.|       :|.:.|....  |.|.:|:.:::::..:.:|::|
  Fly   244 IFD--------------SAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWTDDEI 294

Human   319 RAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTM 383
            .|:...|.|...:..::.:....|.|..:|:.|||..:|:.|..|......:.:|.:.::.::.|
  Fly   295 VAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDM 359

Human   384 CLKESLRLHPPIPTFARGCTQDVVLPDS--------RVIPKGNVCNINIFAIHHNPSVWPDPEVY 440
            .:.||||.........|.|::|..|.|.        :|   |:..||.|..:|.:...:|:|..:
  Fly   360 VISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKV---GDRINIPISGLHLDDRYFPEPRKF 421

Human   441 DPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIV 505
            ||.||..|......|..::||..|||||||.::|:.::|.:|...||.::|   ...||...::.
  Fly   422 DPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKI---EASPRTIKDLW 483

Human   506 LRA-------EDGLWLRVEP 518
            ..|       ..|.|:.:.|
  Fly   484 GSASGFNFTPRSGFWMHLVP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	114/482 (24%)
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	113/479 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810