Protein Alignment KLF12 and CG42741

DIOPT Version :10

• Sequence 1: XP_011533209.1
• Gene: KLF12 / 11278
• HGNCID: 6346
• Length: 415
• Species: Homo sapiens
• Sequence 2: NP_611747.2
• Gene: CG42741 / 37654
• FlyBaseID: FBgn0261705
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 413
• Identity: 135/413 - (32%)
• Similarity: 171/413 - (41%)
• Gaps: 129/413 - (31%)

Human    68 PLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASAS--------SPS 124
            ||.....:|.|           .|.||||||:...|.|.:..|||.....:||:        .|.
  Fly    11 PLSAKEAEGPP-----------VQVEPVDLSLRSPRASTSHGSSSSSYKFSSANKAVGYSNGKPG 64

Human   125 STSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVA-------SASGVGGQQFLHIIHPVPP 182
            .:|.|||||.         ....||.|||.    |...|       ::|||....|    .|...
  Fly    65 GSSGSSSSSG---------FGAGSAGSSSL----GAFAAQQQQQLYASSGVSKLPF----SPFFA 112

Human   183 SSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLED----------------- 230
            :||...                    .|..:...|:.|.|..|.:.::
  Fly   113 ASPFFF--------------------TYRRISGSGSGNGTGSVSVKQEDNNNSCSYNNGSSSGGA 157

Human   231 ----------------------------GRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVN 267
                                        |.|....:..|.|.|.:...|:|      :.:..|..
  Fly   158 GSAANSMQDYESKFSLLSLFKNPYKFAGGDGQASRKTSPTGGSSKPLASNS------SPSWKSYA 216

Human   268 ETGSTALSIARAVQEVHPSPVSRVRG-NRMNNQKFP-------CSISPFSIESTRRQRRSESPDS 324
            .:||...::       :|:.....|| .|.:|..|.       .|...|:..|........:..|
  Fly   217 GSGSPHAAL-------NPAFGGMGRGATRKDNSSFSGINFGGGGSAFGFTTSSDSMANGGYNDLS 274

Human   325 RKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKP 389
            :.|::|:||.|||:||||||||||||:|||||||||.||||||.|:|||||||||||||||||||
  Fly   275 KNRKVHKCDTEGCDKVYTKSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKP 339

Human   390 FKCADCDRSFSRSDHLALHRRRH 412
            |:|..|.|||||||||:||.|||
  Fly   340 FRCQLCTRSFSRSDHLSLHMRRH 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLF12	XP_011533209.1	KLF12_N	40..237	CDD:410608	46/228 (20%)
		COG5048	<241..414	CDD:227381	89/180 (49%)
		C2H2 Zn finger	332..354	CDD:275368	18/21 (86%)
		C2H2 Zn finger	362..384	CDD:275368	19/21 (90%)
		zf-H2C2_2	376..401	CDD:463886	20/24 (83%)
		C2H2 Zn finger	392..412	CDD:275368	14/19 (74%)
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	62/78 (79%)
		C2H2 Zn finger	282..304	CDD:275368	18/21 (86%)
		C2H2 Zn finger	312..334	CDD:275368	19/21 (90%)
		zf-H2C2_2	326..351	CDD:463886	20/24 (83%)
		C2H2 Zn finger	342..362	CDD:275368	14/19 (74%)