Protein Alignment KLF12 and btd

DIOPT Version :10

• Sequence 1: XP_011533209.1
• Gene: KLF12 / 11278
• HGNCID: 6346
• Length: 415
• Species: Homo sapiens
• Sequence 2: NP_511100.1
• Gene: btd / 31912
• FlyBaseID: FBgn0000233
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 106/396 - (26%)
• Similarity: 155/396 - (39%)
• Gaps: 94/396 - (23%)

Human    50 ESEQGSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEP--------VDLSINKARTSP 106
            :.:|..|....:..:.|..||     ..||..|.|.....:.:.|        ::|...:|.::.
  Fly    79 QQQQQQPQQQQHDFLSAAALL-----SAPPSLSGSSSGSSSGSSPLYGKPPMKLELPYPQASSTG 138

Human   107 TAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQ 171
            ||..:|.:.     |:|||.|.|.|.....|.|   ..|:|::.|:.|.....|..|:|..:.|.
  Fly   139 TASPNSSIQ-----SAPSSASVSPSIFPSPAQS---FASISASPSTPTTTLAPPTTAAAGALAGS 195

Human   172 QFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGK 236
                      |:|.....|...:..........:..:...||.|.....||..
  Fly   196 ----------PTSSSPSSSAASAAAAAAAAAAAAADLGAAAVASAAYGWNTAY------------ 238

Human   237 AQMDPRGLSPRQSKSDSDDDDLPNVTLDS---VNETGSTALSIARAVQEVHPSPVSRVRGNRMNN 298
                 .||.|.:|:       .|.....|   .|..|.::.:...:.||....|.|        :
  Fly   239 -----SGLGPARSQ-------FPYAQYASDYYGNAVGMSSSAAWFSHQERLYQPWS--------S 283

Human   299 QKFPCSISPFSIE----STRRQRRS------------------ESPDSRKRRIHRCDFEGCNKVY 341
            |.:|    .|:.:    .|:.||||                  ..||.|.|:.|.|...||.::|
  Fly   284 QSYP----GFNFDDIAFQTQLQRRSVRCTCPNCTNEMSGLPPIVGPDERGRKQHICHIPGCERLY 344

Human   342 TKSSHLKAHRRTHTGEKPYKCTWEGCTWKFARSDELTRHYRKHTGVKPFKCADCDRSFSRSDHLA 406
            .|:||||.|.|.||||:|:.|.  .|..:|:|||||.||.|.||..:|:.|..|.:.|||||||:
  Fly   345 GKASHLKTHLRWHTGERPFLCL--TCGKRFSRSDELQRHGRTHTNYRPYACPICSKKFSRSDHLS 407

Human   407 LHRRRH 412
            .|::.|
  Fly   408 KHKKTH 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLF12	XP_011533209.1	KLF12_N	40..237	CDD:410608	40/194 (21%)
		COG5048	<241..414	CDD:227381	66/197 (34%)
		C2H2 Zn finger	332..354	CDD:275368	11/21 (52%)
		C2H2 Zn finger	362..384	CDD:275368	11/21 (52%)
		zf-H2C2_2	376..401	CDD:463886	11/24 (46%)
		C2H2 Zn finger	392..412	CDD:275368	10/19 (53%)
btd	NP_511100.1	C2H2 Zn finger	338..357	CDD:275368	10/18 (56%)
		zf-H2C2_2	349..374	CDD:463886	13/26 (50%)
		C2H2 Zn finger	365..385	CDD:275368	11/21 (52%)
		zf-H2C2_2	377..402	CDD:463886	11/24 (46%)
		zf-C2H2	391..413	CDD:395048	10/21 (48%)
		C2H2 Zn finger	393..413	CDD:275368	10/19 (53%)