Protein Alignment DUSP12 and CG10089

DIOPT Version :9

• Sequence 1: NP_009171.1
• Gene: DUSP12 / 11266
• HGNCID: 3067
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_001261803.1
• Gene: CG10089 / 39517
• FlyBaseID: FBgn0036369
• Length: 447
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 64/254 - (25%)
• Similarity: 108/254 - (42%)
• Gaps: 44/254 - (17%)

Human    27 MLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVDSEEPSFKAGPGVEDLWRLFVPALDKPETDLL 91
            |.:|.||||.|......:...|....|:.::.:.......     :.|...|.|.|.|.|:.:|.
  Fly     5 MGKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRL-----LPDKHYLCVMASDTPDQNLS 64

Human    92 SHLDRCVAFIGQARAEGRAVLVHCHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNE 156
            .:...|..||..||.....||:||.||:||||.:..|::|....|.:::|.:.::..:..|..|.
  Fly    65 QYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNA 129

Human   157 GFEWQLKLYQAMGYEVDTSSAIYKQYRL----QKVTEKYPELQNLPQELFAVDPTTVSQGLKD-- 215
            ||:.||:.::              |::|    :::.|::|.     ..|..:|.|.|:..|.:
  Fly   130 GFQSQLQEFE--------------QFKLSEERRRLRERFPS-----SALEQLDRTKVATALDNYQ 175

Human   216 EVLYKCRKCRRSLFRSSSI------LDHREGSGPIAFAHKRMTPSSMLTTGR-QAQCTS 267
            |:|.....|..:..|....      :|..:|    .|   |..||:..|..| :||.::
  Fly   176 ELLQNRDICEGNCSRGEKCPTGVCNMDPTKG----LF---RRRPSNASTHSRLRAQSSN 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUSP12	NP_009171.1	DSPc	26..166	CDD:238073	41/138 (30%)
		Substrate binding. /evidence=ECO:0000305|PubMed:24531476, ECO:0007744|PDB:4KI9	116..121		2/4 (50%)
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	41/138 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1042
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840