Protein Alignment DCTN3 and DCTN3-p24

DIOPT Version :10

• Sequence 1: NP_009165.1
• Gene: DCTN3 / 11258
• HGNCID: 2713
• Length: 186
• Species: Homo sapiens
• Sequence 2: NP_652036.1
• Gene: DCTN3-p24 / 46074
• FlyBaseID: FBgn0010622
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 183
• Identity: 49/183 - (26%)
• Similarity: 84/183 - (45%)
• Gaps: 7/183 - (3%)

Human     7 LQRLQARVEELERWVYGP-GGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDP 70
            |..|:.|::.|.| |.|| ..:.....|.|.|......||..::....::...|:.::|.|||||
  Fly     4 LDILEKRIDALTR-VLGPVQDSEVGEGVVDALCSAHAILGEATTGSAALQQCVKRSDELEKYLDP 67

Human    71 EYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP-EHAARLQRLAQIHI 134
            .:::... ...||..::.|....:.:|...||::..|.|.|.:.:.:::| |...:|:.:.|.:.
  Fly    68 NFLEEHQ-QVRSKEVYLQAVAPELHTQAEQLERIKQLEPALGAEYFRSIPAECLEQLKGITQNNG 131

Human   135 QQQDQCVEITEESKAL-LEEYNKTTMLLSKQFVQWDELLCQL-EAATQVKPAE 185
            :...|. |:.|||..| ::.|.:....|........|.|.|: |...|.|.||
  Fly   132 EYAQQS-ELIEESLVLAMKRYGEIQAGLLSSLDAMSERLDQVEERMEQRKRAE 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCTN3	NP_009165.1	Dynactin_p22	10..170	CDD:462162	40/162 (25%)
DCTN3-p24	NP_652036.1	Dynactin_p22	7..151	CDD:462162	38/146 (26%)