Protein Alignment SNX18 and Snx18

DIOPT Version :10

• Sequence 1: XP_047272635.1
• Gene: SNX18 / 112574
• HGNCID: 19245
• Length: 659
• Species: Homo sapiens
• Sequence 2: NP_001101122.1
• Gene: Snx18 / 310097
• RGDID: 1310367
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 593/659 - (89%)
• Similarity: 598/659 - (90%)
• Gaps: 44/659 - (6%)

Human     1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAPEPG 65
            |||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||
  Rat     1 MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVIRAPEPG 65

Human    66 PAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQPPGAGFPYGG 130
            |..||||||||||||||||||||||.||||:|:|       |||||.:  |.:||.|||||.|||
  Rat    66 PPADGGPGAPARYANVPPGGFEPLPAAPPAAFQP-------LLQPQAS--PGSFQSPGAGFTYGG 121

Human   131 GALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGVGAAGRYRL 195
            ||.|||||||||.||||.||||||||||||||||||||||||||||||||||||||.||||||||
  Rat   122 GAPQPSPQQLYGAYQASLGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGGGAAGRYRL 186

Human   196 STRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCV 260
            ||||||||||||.|.||.|..||.|||||||||||||||||||||||||||||||||||||||||
  Rat   187 STRSDLSLGSRGVSAPPPHQASGAKSSATVSRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCV 251

Human   261 VLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAE 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   252 VLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAE 316

Human   326 KFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAW 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   317 KFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAW 381

Human   391 KQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARK 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   382 KQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARK 446

Human   456 QVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMD 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   447 QVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMD 511

Human   521 LLALYQGHLANFPDIIHVQKGKAWPLEQVIWSVLCRLKGATLTAVPLWVSESYSTGALTKVKESR 585
            ||||||||||||||||||||                                   ||||||||||
  Rat   512 LLALYQGHLANFPDIIHVQK-----------------------------------GALTKVKESR 541

Human   586 RHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLE 650
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   542 RHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLE 606

Human   651 EALHKYDSV 659
            |||||||||
  Rat   607 EALHKYDSV 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNX18	XP_047272635.1	SH3_SNX18	4..58	CDD:212830	52/53 (98%)
		PHA01929	<81..>138	CDD:177328	37/56 (66%)
		PX_SNX18	276..403	CDD:132819	126/126 (100%)
		BAR_SNX18	415..656	CDD:153354	205/240 (85%)
Snx18	NP_001101122.1	SH3_SNX18	4..58	CDD:212830	52/53 (98%)
		PX_SNX18	267..394	CDD:132819	126/126 (100%)
		BAR_SNX18	406..612	CDD:153354	205/240 (85%)