Protein Alignment RASSF8 and meru

DIOPT Version :9

• Sequence 1: NP_001158218.1
• Gene: RASSF8 / 11228
• HGNCID: 13232
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_001246779.1
• Gene: meru / 39727
• FlyBaseID: FBgn0052150
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 78/408 - (19%)
• Similarity: 159/408 - (38%)
• Gaps: 73/408 - (17%)

Human     2 ELKVWV-DGVQRIVCGVTEVTTCQEVVIALAQAIGRTGR-------------------------Y 40
            |:.:|: ||..|.|.|||..|||.:::.||.....|.|.                         |
  Fly   124 EIPIWMDDGEARYVSGVTNKTTCDDIIKALIDDELRNGNGFYCGNNPKDGGQRKTAAASRDYSDY 188

Human    41 TLIEKWRDTERHLAPHENPIISLNKWGQYASDVQLILRRTG-----------PSLSERPTSDSVA 94
            .:.|.|...||....:...:.....|.:..:::::.|:...           |. |:..|..|:.
  Fly   189 IITESWGGIERCYDGNMAILPVWRAWSRVHNELRISLKHRDSFRDPLAMQLVPH-SQSATGFSMY 252

Human    95 RIPERTLY----RQSLPPLAKLRPQIDKSIKRREPKRKSLTFTGGAKGLM--DIFGKGKETEFKQ 153
            :..::.|:    :::.|...|..|::...:|.:....:..|.|.....::  |...:|.|...|.
  Fly   253 KWLKKLLHLKKGKKTPPKPTKTPPKVPNKLKEKRVHGQKQTMTNDLVLVIMPDQLYRGTENTAKS 317

Human   154 KVLNNCKTTADELKKLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDV 218
            |:.   |...:.:.|....:..:.:..:..:|:....|.......|.|:...|.|.:.|..||.|
  Fly   318 KLY---KLAENRVSKQRHRRRSRHEITKASVETFRTAIPSECNNNNYNVNNCIRRRKDKPLRNSV 379

Human   219 EIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQREVQE 283
            ..:.... ..::.:..|.|..|..||.|: .::...:|:      :.:..|..|...:||:.::.
  Fly   380 RYKLASL-HADMNVRYEKEHALTRQLSEM-CRLYRLQNE------RYKGPEMELSVGQLQQNIEA 436

Human   284 AQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIK-----------AVERSLGQATKRLQDKEQ-- 335
            ...:..:.:.::.::|.||    :..:.|.|.:|           |.::...:.|..||:.|.
  Fly   437 YAEDIIKTEHELLELKNEI----KHDISLINNLKRLTLEESEADAACKKGAAKITHPLQENENTP 497

Human   336 ELEQLTKELRQV-NLQQF 352
            ::.:.|:|::.| |:.:|
  Fly   498 QVAKNTQEMQFVDNIYEF 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_001158218.1	RA_RASSF8	2..83	CDD:340551	23/117 (20%)
		Smc	<160..>351	CDD:224117	38/204 (19%)
meru	NP_001246779.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1574
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15286
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000