Protein Alignment RASSF8 and CG13875

DIOPT Version :10

• Sequence 1: NP_001158218.1
• Gene: RASSF8 / 11228
• HGNCID: 13232
• Length: 419
• Species: Homo sapiens
• Sequence 2: NP_612005.1
• Gene: CG13875 / 38024
• FlyBaseID: FBgn0035104
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 94/469 - (20%)
• Similarity: 176/469 - (37%)
• Gaps: 127/469 - (27%)

Human     5 VWVDGVQRIVCGVTEVTTCQEVVIAL------------AQAIGRTGRYTLIEKWRDTERHL---- 53
            :||:|.:..:.|....|||.:::.||            .:.|....::.:::|.|..|.:|
  Fly    24 IWVNGEEHWISGADSSTTCADLICALISYQIDQKHVLSKEEILAPQQFAIVQKQRHYEEYLDSSA 88

Human    54 -------APHENPIISLNKWGQYASDVQLILRRTGPSLSER-PTSDSVARIPERTLYRQSLPPLA 110
                   :||..|          ..:.||.||....|..:: ||:|..                :
  Fly    89 RLLDVITSPHAMP----------KEEYQLHLRHLATSSRKQVPTTDKD----------------S 127

Human   111 KLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELKKLIRLQTE 175
            .:...:|.|...|..:|..|..|   |...:|..|..:...||:..|:..|..:.|..:|..|.|
  Fly   128 GMGSPVDSSRSMRIRRRGKLLST---KTTDNINTKQSKRSRKQQQRNHHLTPNESLLTIILAQDE 189

Human   176 -----------------KLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEE 223
                             |::..:.|:...|:...:..:.|..:|:      |.:.|..|:|:.||
  Fly   190 TILQQMTMLHEKDRQIFKIEEEKHQVRERELGKNYLLETYLKDLD------EPQEKGEDLELFEE 248

Human   224 EFWENELQIEQE-------------NEKQLKDQ-----LQEIRQ--KITECENKLKDYLAQIRTM 268
               ...:.::::             |...::|.     |::|.:  |..:||.:|.
  Fly   249 ---MTHIDVDRDFGIMSDSTVQTALNSGTMQDDIRLYWLEKIHEVNKELQCEEELL--------- 301

Human   269 ESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDK 333
             ..|.::..:.:|:.|...:.||..:|.::..|:..|...       |..|||.|..|.::|:.|
  Fly   302 -LSLHSKVRRHQVKRAYQTKSEVLLQIERLDTELATQVAD-------IHHVERKLFTANEQLKAK 358

Human   334 EQELEQLTKELRQV---NLQQFIQQTGTKVTVLPAEPIEIEASHADIEREAPFQSGSLKRPGSSR 395
            ...||.|::|....   .:|:....||:..:.      :::.|.:|..:.|......:||..::.
  Fly   359 LAVLECLSREFETTVSGGVQEGDVATGSNASA------KVQQSQSDDLQHAGNWLHVVKRLFAAD 417

Human   396 QLPSNLRILQNPIS 409
            .|  |.|:.|..:|
  Fly   418 HL--NRRLTQQALS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASSF8	NP_001158218.1	RA_RASSF8	2..83	CDD:340551	21/100 (21%)
		SMC_prok_B	<164..>384	CDD:274008	49/259 (19%)
CG13875	NP_612005.1	Ubl1_cv_Nsp3_N-like	24..111	CDD:475130	20/96 (21%)