DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DUSP10 and CG10089

DIOPT Version :9

Sequence 1:	NP_009138.1	Gene:	DUSP10 / 11221	HGNCID:	3065	Length:	482	Species:	Homo sapiens
Sequence 2:	NP_001261803.1	Gene:	CG10089 / 39517	FlyBaseID:	FBgn0036369	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	53/148 - (35%)
Similarity:	80/148 - (54%)	Gaps:	15/148 - (10%)

- Green bases have known domain annotations that are detailed below.

Human   319 NAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTH------LPLYHYEKGLFNYKRLPATD 377
            |..:..:||.|::||.:|::|...::|..|.::|.:  |      ||..|       |..:.|:|
  Fly     2 NWHMGKVLPGLYVGNYRDSKDHAQLERFKISHIIAI--HDSPRRLLPDKH-------YLCVMASD 57

Human   378 SNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 442
            :..|||.|||....:||..|......:||||.||:|||.|:.:||:|..|.:...:|.|.|:..|
  Fly    58 TPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGR 122

Human   443 PIISPNLNFMGQLLEFEE 460
            .:.:||..|..||.|||:
  Fly   123 AVANPNAGFQSQLQEFEQ 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DUSP10	NP_009138.1	DSP_MapKP	149..284	CDD:238723
		Interaction with MAP kinases	199..215
		DSPc	321..459	CDD:238073	50/143 (35%)
CG10089	NP_001261803.1	DSPc	4..139	CDD:238073	50/143 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1716
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1576308at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820