| Sequence 1: | NP_009128.1 | Gene: | FZD10 / 11211 | HGNCID: | 4039 | Length: | 581 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_570992.2 | Gene: | fzd10 / 30366 | ZFINID: | ZDB-GENE-990415-220 | Length: | 580 | Species: | Danio rerio |
| Alignment Length: | 567 | Identity: | 440/567 - (77%) |
|---|---|---|---|
| Similarity: | 496/567 - (87%) | Gaps: | 4/567 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 16 GSCAAISSMDMERPGDGKCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCH 80
Human 81 GHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNY 145
Human 146 LCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCDNPGKFHHVEKSASCAPL 210
Human 211 CTPGVDVYWSREDKRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSV 275
Human 276 GYLIRLFAGAESIACDRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGK 340
Human 341 KWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACY 405
Human 406 LVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLNMD 470
Human 471 YWKILAAQHKCKMNNQTKTLDCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQQVC 535
Human 536 SRRLKKKSRRKPASVITSGGIYKKAQHPQKTHHGKYEIPAQSP-TCV 581 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FZD10 | NP_009128.1 | CRD_FZ10 | 30..156 | CDD:143571 | 106/125 (85%) |
| 7tmF_FZD10 | 217..535 | CDD:320165 | 266/317 (84%) | ||
| TM helix 1 | 226..251 | CDD:320165 | 18/24 (75%) | ||
| TM helix 2 | 260..281 | CDD:320165 | 17/20 (85%) | ||
| TM helix 3 | 310..336 | CDD:320165 | 22/25 (88%) | ||
| TM helix 4 | 353..369 | CDD:320165 | 14/15 (93%) | ||
| TM helix 5 | 391..420 | CDD:320165 | 24/28 (86%) | ||
| TM helix 6 | 440..467 | CDD:320165 | 25/26 (96%) | ||
| TM helix 7 | 497..522 | CDD:320165 | 24/24 (100%) | ||
| Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members. /evidence=ECO:0000250 | 526..531 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 560..581 | 9/21 (43%) | |||
| PDZ-binding | 579..581 | 1/1 (100%) | |||
| fzd10 | NP_570992.2 | CRD_FZ | 31..157 | CDD:382974 | 106/125 (85%) |
| 7tmF_FZD10 | 217..535 | CDD:320165 | 267/318 (84%) | ||
| TM helix 1 | 226..251 | CDD:320165 | 18/24 (75%) | ||
| TM helix 2 | 260..281 | CDD:320165 | 17/20 (85%) | ||
| TM helix 3 | 310..336 | CDD:320165 | 22/25 (88%) | ||
| TM helix 4 | 353..369 | CDD:320165 | 14/15 (93%) | ||
| TM helix 5 | 391..420 | CDD:320165 | 24/28 (86%) | ||
| TM helix 6 | 440..467 | CDD:320165 | 25/26 (96%) | ||
| TM helix 7 | 496..521 | CDD:320165 | 24/24 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C194336586 | |
| Domainoid | 1 | 1.000 | 569 | 1.000 | Domainoid score | I1969 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3577 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H21411 | |
| Inparanoid | 1 | 1.050 | 926 | 1.000 | Inparanoid score | I2679 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG50792 | |
| OrthoDB | 1 | 1.010 | - | - | D145274at7742 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0013181 | |
| OrthoInspector | 1 | 1.000 | - | - | oto49631 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_108212 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11309 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R10868 |
| SonicParanoid | 1 | 1.000 | - | - | X126 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 19 | 19.300 | |||||