Protein Alignment SUPT16H and supt16h

DIOPT Version :10

• Sequence 1: NP_009123.1
• Gene: SUPT16H / 11198
• HGNCID: 11465
• Length: 1047
• Species: Homo sapiens
• Sequence 2: NP_001091053.1
• Gene: supt16h / 562348
• ZFINID: ZDB-GENE-031118-96
• Length: 1033
• Species: Danio rerio
• Alignment Length: 1051
• Identity: 880/1051 - (83%)
• Similarity: 967/1051 - (92%)
• Gaps: 23/1051 - (2%)

Human     1 MAVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTI 65
            |||:|||||:|||:||||.||:|||||:..|||||||||||||||||||||||||||||||||||
Zfish     1 MAVSLDKDAFYRRIKRLYGNWKKGEDEFGKVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTI 65

Human    66 MVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKN 130
            ||||:.||||:|||||||||||:|.|||||||||.|.||||:||||||||.:||||||||:.||.
Zfish    66 MVFCESKIIFLASKKKVEFLKQVAVTKGNENANGVPPITLLVREKNESNKVNFDKMIEAIRGSKE 130

Human   131 GKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFN 195
            ||.:|||.|||||||:||||:|.:..||..|:|||.|||||:||||||||.|||||||||::||:
Zfish   131 GKTVGVFIKDKFPGEYMKSWSDTITAEGLQKVDISTVVAYTMAVKEDGELALMKKAASITTDVFS 195

Human   196 KFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVV 260
            |||||||||||||||||:||:||||||||||::|:|.|.|||||||||||||||||||:||||||
Zfish   196 KFFKERVMEIVDADEKVKHSRLAESVEKAIEDRKFLGGVDPSTVEMCYPPIIQSGGNYSLKFSVV 260

Human   261 SDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDV 325
            ||||||||||||||||||:||||||||||||||||||:|:|||||||::||||||::||||:.:.
Zfish   261 SDKNHMHFGAITCAMGIRYKSYCSNLVRTLMVDPSQEMQDNYNFLLQVEEELLKEMKHGVKLSEA 325

Human   326 YNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKE 390
            |||||:.|||:||:|::|:||||||.|||||||||||||.|||:|||:||||||:|||:|:.|||
Zfish   326 YNAVMEFVKKEKPDLVSKLTKNLGFAMGIEFREGSLVINQKNQFKLKRGMVFSISLGFADMINKE 390

Human   391 GKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFLKNEDEEEEEEEKDEAEDLLGRGS 455
            |||.|:|.||||||||:.::|:..|||||.||||:|||||||||:||:|:|||.|.||:|||:|:
Zfish   391 GKKEEQKKYALFIGDTIQINEEDQATVLTPVKKKIKNVGIFLKNDDEDEDEEEGDNAEELLGKGA 455

Human   456 R-AALLTERTRNEMTAEEKRRAHQKELAAQLNEEAKRRLTEQKGEQQIQKARKSNVSYKNPSLMP 519
            | ||||.:|||||||||||||.||||||.|:|||||||||||||.|||||.|||||||||.|.||
Zfish   456 RSAALLADRTRNEMTAEEKRRTHQKELANQVNEEAKRRLTEQKGGQQIQKVRKSNVSYKNVSQMP 520

Human   520 KEPHIREMKIYIDKKYETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFYCPGSALGRNEG 584
            ||..||:|||:||||:|||||||||||||||||||||||||||||||||||||:.|||:|||:||
Zfish   521 KEKDIRDMKIFIDKKHETVIMPVFGIATPFHIATIKNISMSVEGDYTYLRINFFVPGSSLGRHEG 585

Human   585 NIFPNPEATFVKEITYRASNIKAPGEQTVPALNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQD 649
            ||||||||||||||||||||:|:||:.:||:.|||||||||||||||||||||||||||||||||
Zfish   586 NIFPNPEATFVKEITYRASNLKSPGDHSVPSTNLQNAFRIIKEVQKRYKTREAEEKEKEGIVKQD 650

Human   650 SLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHVNGFRFTSVRGDKVDILYNNIKHALFQPCDG 714
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||:||||||
Zfish   651 SLVINLNRSNPKLKDLYIRPNIAQKRMQGSLEAHTNGFRFTSVRGDKVDILYNNIKHAIFQPCDG 715

Human   715 EMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKTA 779
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|
Zfish   716 EMIIVLHFHLKNAIMFGKKRHTDVQFYTEVGEITTDLGKHQHMHDRDDLYAEQMEREMRHKLKSA 780

Human   780 FKNFIEKVEALTKEELEFEVPFRDLGFNGAPYRSTCLLQPTSSALVNATEWPPFVVTLDEVELIH 844
            |||||||||:|||||||||||||||||.|||||||||||||||:|.|.|||||||||||||||:|
Zfish   781 FKNFIEKVESLTKEELEFEVPFRDLGFQGAPYRSTCLLQPTSSSLCNVTEWPPFVVTLDEVELVH 845

Human   845 FERVQFHLKNFDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTI 909
            ||||||||||||:|||||||:||||||||:||.|||||||||||||:|||||:||||||||||||
Zfish   846 FERVQFHLKNFDVVIVYKDYNKKVTMINAVPVNSLDPIKEWLNSCDIKYTEGIQSLNWTKIMKTI 910

Human   910 VDDPEGFFEQGGWSFLEPEGEGSDAEEGDSESEIEDETFNPSEDDYEEEEEDSDEDYSSEAEESD 974
            ||||||||||||||||:||.|||..|| ||||||||||||||.|:.||||||||||||||.|:||
Zfish   911 VDDPEGFFEQGGWSFLDPESEGSGGEE-DSESEIEDETFNPSADEEEEEEEDSDEDYSSETEDSD 974

Human   975 YSKESLGSEEESGKDWDELEEEARKADRESRYEEEEEQSRSMSRKRKASVHSSGRGSNRGSRHSS 1039
            || .||||||||||||||||||||||||||:|||.||.|   :||||      ||        ||
Zfish   975 YS-ASLGSEEESGKDWDELEEEARKADRESQYEEVEETS---NRKRK------GR--------SS 1021

Human  1040 APP---KKKRK 1047
            |||   ||||:
Zfish  1022 APPPRSKKKRR 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SUPT16H	NP_009123.1	COG5406	5..1001	CDD:227693	851/996 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	492..518		22/25 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	918..1047		95/131 (73%)
supt16h	NP_001091053.1	COG5406	3..1005	CDD:227693	857/1003 (85%)