Protein Alignment CHKA and eas

DIOPT Version :9

• Sequence 1: NP_001363148.1
• Gene: CHKA / 1119
• HGNCID: 1937
• Length: 467
• Species: Homo sapiens
• Sequence 2: NP_523364.2
• Gene: eas / 32585
• FlyBaseID: FBgn0000536
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 487
• Identity: 115/487 - (23%)
• Similarity: 191/487 - (39%)
• Gaps: 165/487 - (33%)

Human    75 PQPPADE--------------QPEPRTRRRAYLWCKEFLP------GAWRGLRE---------DE 110
            |.|...|              :||.::|:.|.:   .|:|      ...:|.:|         |.
  Fly    62 PNPSGSENKNENEQNSRDIRAKPEDKSRKEAIV---PFVPIFVEEADVIQGAKELLKVIRPTWDL 123

Human   111 FHISV--IRGGLSNMLFQC---------------SLPDTTATL----GDEP-------------- 140
            .|:..  ...|::|.|..|               .||..|..|    .::|
  Fly   124 SHVEFKSFTDGITNKLVGCFHKEISKLNDENGGSYLPIKTQGLSPVQSEDPVIIEKEDDDEFTDD 188

Human   141 -------------RKVLLRLYGAILQMVFLIKLWNGKRSCNKEGSEQAQKENEFQGAEAMVLESV 192
                         ..||:|:||....::.               ..:|:.:|
  Fly   189 RAADDGSPVQYSDNVVLVRIYGNKTDLLI---------------DRKAETQN------------- 225

Human   193 MFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFH----------- 246
             |.:|....|.|.||..|..|.:.:::|...|:|:.:..|:|...:|.:||..|
  Fly   226 -FLLLHTYGLAPSLYATFKNGLVYEYVPGTTLNTDSVLCPEIWPLVARRMAEMHRKVRKHGDSSA 289

Human   247 --GMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPL-----ELENLRSLLE 304
              .|.|.:.|...:|         :::..:|::..:.|::.:..   ||:     |...|...||
  Fly   290 TKPMPMIWKKTQSFL---------DLVPERFSDAEKHKRVKETF---LPIGRLREEFNKLYEYLE 342

Human   305 STPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWM----YDYS 365
            :..||:||.|||...||::..:....     :..||:||:.||::.|||||||.|..    .|||
  Fly   343 ALDSPIVFSHNDLLLGNVIYTQSLNT-----VNFIDYEYADYNFQAFDIGNHFAEMCGVDEVDYS 402

Human   366 YEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW 430
                        :||.::.||.::..||..:... .|:..:|    .|.:.::||:||||||..|
  Fly   403 ------------RYPKREFQLQWLRVYLEEYLQR-SNIQNDE----VELLYVQVNQFALASHIFW 450

Human   431 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQK 462
            .:||::||:.|:|:|.|:.||..|::.|..:|
  Fly   451 TVWSLLQAEHSTIDFDYVGYAFLRYNEYLARK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHKA	NP_001363148.1	ChoK_euk	111..462	CDD:270705	102/420 (24%)
eas	NP_523364.2	ETNK_euk	126..478	CDD:270706	100/414 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3046
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000493
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.760