Protein Alignment MAP4K5 and ppk11

DIOPT Version :10

• Sequence 1: XP_047286846.1
• Gene: MAP4K5 / 11183
• HGNCID: 6867
• Length: 863
• Species: Homo sapiens
• Sequence 2: NP_594517.1
• Gene: ppk11 / 2541473
• PomBaseID: SPAC2C4.14C
• Length: 312
• Species: Schizosaccharomyces pombe
• Alignment Length: 325
• Identity: 125/325 - (38%)
• Similarity: 182/325 - (56%)
• Gaps: 29/325 - (8%)

Human    17 QQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLE-PGDDFSLIQQEIFMVKECKHCNIVAY 80
            :..|..:|.:|.|::|.|::|::|.:.::.|:|::.|: ..|....:.|||..:.:....:|..|
pombe     3 KHQYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKY 67

Human    81 FGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGAN 145
            :.|::...:|||.||||.|||..|:..::|..||..||.|.|:.|:.|.|||.:||||||||.||
pombe    68 YASFVDGFRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAAN 132

Human   146 ILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIE 210
            ||....|.||||||||:.::.:...|...|:|||:||||||.   |..|||...|||::||||.|
pombe   133 ILTMKDGLVKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVV---KQTGYNYKADIWSLGITAYE 194

Human   211 LGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHT 275
            |...:||...:|||:.|.|:.|.:  ||.| :::|:|..|.:||...|.||||.|.|||.|..|.
pombe   195 LATGEPPYSGIHPMKVLLLIPKHS--PPSL-ERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHK 256

Human   276 FVAQ--PGLSRALAVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEIN 338
            |:.:  |..|....|            |.|.:..:.:..|.|        |..|:....:|:.|:
pombe   257 FIKKYCPNTSVKEVV------------ASYAKWKESELLPEA--------TPYNSTMGNSANTID 301

Human   339  338
            pombe   302  301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP4K5	XP_047286846.1	STKc_MAP4K5	10..277	CDD:270813	113/260 (43%)
		CNH	528..843	CDD:214481
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	119/291 (41%)