Protein Alignment SLC2A6 and CG17930

DIOPT Version :10

• Sequence 1: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Sequence 2: NP_650533.1
• Gene: CG17930 / 41979
• FlyBaseID: FBgn0038416
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 113/547 - (20%)
• Similarity: 196/547 - (35%)
• Gaps: 131/547 - (23%)

Human    10 GPDYDTF------PEKPPPSPGDRARVGTLQNKR---------VFLATFAAVLGNFSFGYALVYT 59
            ||...|:      .:.|||.|.....:.|..|.|         ...||...|.........|.:.
  Fly    22 GPQQTTYITNGRQQQPPPPPPPTTVIITTQSNSRWATPTQTQSGTAATLLFVYAGMDMAQGLGWN 86

Human    60 SPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDL----LGRKLSIMFSAVPSA 120
            ...:.|         :..:.|.|||..|. :||....:::..|..:    ||..::::.:.:..:
  Fly    87 LTAVSA---------NTLEFQYSWFIGVI-IGAVVSAITSAFLPKIVFYGLGGVMNLIDAIIFVS 141

Human   121 AGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRG----------ALGATPQL 175
            |.|...:       :|..|.:.|...||......::.:|||....||          |||...|:
  Fly   142 APYEYES-------ILAARYVGGVGIGLITVPFLIHSAEIASSTNRGTCCALEQYGLALGVAIQV 199

Human   176 MAVFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWLRGT 240
              ::.|.....||:.:. |...:.|.....|.:..::...:||.|.:.:.::::|..::..|.|:
  Fly   200 --IYDSQWSQGLGMTIN-RVHGIFGIVFTAIALGSVAITIDSPIFYIRQNQEQKARASVKQLMGS 261

Human   241 DVDVHWEFEQIQDNVRRQSSRVSWAEARAPHV--------------CRPITVALLMRLLQQLTGI 291
                :|         .|::...::.||:...|              ..|....||.|.....|..
  Fly   262 ----YW---------TREAGDRAYDEAKLYVVEGSAQGVGEQLGESMMPFLKLLLFRCFVAFTFS 313

Human   292 TPI---LVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVS-AAIMFAA 352
            .|:   ::....:.:.|....|    ..|.|.:||:..||....:|..|||   ||| ..:|..|
  Fly   314 VPLSYSILTTTELVEGTLHSWP----TIIFGLLRLIGALITFAVLDTVGRK---FVSLLGLMCMA 371

Human   353 NLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYL-------TLVPLLATMLFIMGYA 410
            .|.||:              ||:    :||.        |::       .:..|.....|..|:.
  Fly   372 GLMLGM--------------AGV----YGDY--------GHIFDDYFMWQVCRLGMAFQFFAGFF 410

Human   411 VGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAA---IC 472
            :   ..:...:.|..|:|.:....||.|....:...::...|:|....:     :.:|.|   |.
  Fly   411 I---CSSSAYLGEAFPMRVKPFLIGLIVCLEQVIHIIVIVKFVPTAEFY-----YTYFVAVGIIM 467

Human   473 LVSLVFTGCCVPETKGRSLEQIESFFR 499
            ::.||.....:|||:|.:|.|....||
  Fly   468 VIGLVAFAVLMPETRGLTLRQAGERFR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		7/23 (30%)
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	100/495 (20%)
CG17930	NP_650533.1	MFS	98..488	CDD:475125	95/454 (21%)