back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SLC2A6 and CG6901

DIOPT Version :10

Sequence 1:	NP_060055.2	Gene:	SLC2A6 / 11182	HGNCID:	11011	Length:	507	Species:	Homo sapiens
Sequence 2:	NP_650531.1	Gene:	CG6901 / 41977	FlyBaseID:	FBgn0038414	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	121/525 - (23%)
Similarity:	194/525 - (36%)	Gaps:	100/525 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     2 QEPLLGAEGPDYDTFPEKPPPSPGDR---ARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVI 63
            ||.::.|..|..:  |.||..:..:|   .|:.. ||...:...|..:.|......:|.::.|..
  Fly    14 QETIIIATAPPPE--PRKPAVTTNNRGYFTRINK-QNYASYTVFFLFIYGGMDMAASLGWSQPYS 75

Human    64 PALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLL----GRKLSIMFSAVPSAAGYA 124
            ..|         .|:....||..|. :||.|..|:...|..|:    |..:.:..|.:.:||.|:
  Fly    76 VLL---------FTEYSYCWFVGVI-IGALATTLTMSFLPKLVYYVFGALMQLTGSIIFTAADYS 130

Human   125 LMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL 189
                     ..|..|.|.|...||......::.:|:|...:||..|...|.....|..    ..:
  Fly   131 ---------ACLAARYLAGLGIGLITVPFLIHNAEVASNNLRGVNGGMEQCGLALGIF----FQV 182

Human   190 LLPWRWLAVAGEAP-----------VLIMILLLSFMPNSPRFLLSRGRDEEALRAL-AWLRGTDV 242
            :....|.::....|           .|..:.:.:.:..||.|.|.|..:..|.::. ..||....
  Fly   183 IFTTEWTSLIDSNPNEIHGIIGIVVSLFGLAMTALVVESPIFFLRRNMENRAQQSQEKLLRHNPG 247

Human   243 DVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAV 307
            .|....::.:..|....:|....|..|.  ..|....||.|.....:...|:.:   ||..||||
  Fly   248 GVSAALKEARRYVAESDNRTLGEELVAS--VMPFLKMLLFRCFVAFSFSLPLTM---SIISSTAV 307

Human   308 ------LLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRP 366
                  |.|    ..:.|.:|::.|::|.:.:|..|||.:..|...:|  |.|.|||
  Fly   308 AEKGLSLWP----IYLFGVLRVIGVMVALIFLDTLGRKAVSLVGLLVM--AGLMLGL-------- 358

Human   367 LSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARG 431
                  |||.:.....::..|...|..:.|...:...||:...:.        .|.|..|:|.:.
  Fly   359 ------AGLYANVTNLISFNLMTSACNIALAFQVFAGLFVCSSSA--------YMGEAFPMRVKS 409

Human   432 VASGLCVLASWLTAFVLTKSFLPVVSTFGLQVP---FFF--FAA---ICLVSLVFTGCCVPETKG 488
            ...|:.|:...:...|:    :..||:    ||   |||  |.|   |.||.::|....:||||.
  Fly   410 FLVGVIVIIEQIVHIVV----IACVSS----VPNKDFFFQYFLAVGIIMLVGMIFFTVSMPETKK 466

Human   489 RSLEQ 493
            .:|.:
  Fly   467 MTLRK 471

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.