Protein Alignment SLC2A6 and CG14606

DIOPT Version :10

• Sequence 1: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Sequence 2: NP_001334690.1
• Gene: CG14606 / 40866
• FlyBaseID: FBgn0037485
• Length: 466
• Species: Drosophila melanogaster
• Alignment Length: 485
• Identity: 127/485 - (26%)
• Similarity: 216/485 - (44%)
• Gaps: 46/485 - (9%)

Human    24 PGDRARVGTLQNKRVFLATFAAVLGNFSFGYALVYTSPVIPAL---ERSL-DPDLHLTKSQASWF 84
            |..:..|.:::.:..|:||....:...:.|.|:.:.||.:..|   |..| ||   ||.:||||.
  Fly     5 PSQKLSVFSVRYRWQFIATMTVHIMTLTHGIAVGWLSPSLRLLASDESPLGDP---LTITQASWV 66

Human    85 GSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLT 149
            ||:..||:..|.:...:|.|.||||:.:.|.|:|:...:.|:..|..:..|..||.|.|.:||..
  Fly    67 GSLIGLGSLTGNIIFGLLLDRLGRKVCMYFLAIPNMIYWILIYSAQDVTYLYAGRFLAGMSGGGC 131

Human   150 AACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWL-AVAGEAPVLIMILLLSF 213
            ...:|::::|||...|||||.:...:....|.:..:.|...||:..: .:....||:.|:.::.
  Fly   132 YVVLPIFIAEIADNSVRGALSSMAMMYVSIGMMVGFTLASYLPYYLMPCIIVALPVVFMLSVIG- 195

Human   214 MPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQ--------DNVRRQ------SSRVSW 264
            :..:|::||.||||::|.::..:.:........:.|..|        |..|.|      :..:||
  Fly   196 LSETPQYLLRRGRDDQAEKSFYFYKNLTPPTSSDKEASQHDAAKIEFDTFRLQVLSGGVTESISW 260

Human   265 AEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIA 329
            .:.......:...:..::.:..||:|...|..|...||......|.|.....:|||.:|:.:..|
  Fly   261 RDFINVPTLKIFGLIFVLIICNQLSGSFAIFNYTSHIFAELGNNLDPNTSTIVVGAAQLVGIFSA 325

Human   330 ALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYL 394
            .:.:|..||:|||..|...|....|.:.|...|.       |...|....|        .|...:
  Fly   326 VVLVDRLGRRVLLLTSMGGMGLGELAIALLKCFA-------SDEFLNQNGW--------LPLVIM 375

Human   395 TLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTF 459
            .||..:|::        |...:.::::.|:||.:.|.:.:.|.:.......||..|.:..::...
  Fly   376 CLVACIASL--------GVIALIFIIIIELLPAKIRSIGTSLSMATFSGFIFVALKIYPTMIYDQ 432

Human   460 GLQVPFFFFAAICLVSLVFTGCCVPETKGR 489
            ||....|..|.:||...:..|..:|||||:
  Fly   433 GLAATMFMSAGMCLFGFIVLGLFLPETKGK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		1/3 (33%)
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	125/470 (27%)
CG14606	NP_001334690.1	MFS_GLUT6_8_Class3_like	20..466	CDD:340916	125/470 (27%)