Protein Alignment SLC2A6 and CG32053

DIOPT Version :10

• Sequence 1: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Sequence 2: NP_729587.1
• Gene: CG32053 / 39178
• FlyBaseID: FBgn0052053
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 119/544 - (21%)
• Similarity: 192/544 - (35%)
• Gaps: 120/544 - (22%)

Human    18 EKPPPSPG------------------DRARVGTLQNKR-----------------VFLATFAAVL 47
            |:|.|..|                  ||.|...|||.:                 |..|....:.
  Fly     4 ERPSPDDGFHVVPIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLT 68

Human    48 GNFSFGYALVYTSPVIPALERSLDPDLHLTKS-QASWFGSVFTLGAAAGGLSAMILNDLLGRKLS 111
            |.....:::.:.|.:         .:|.:|.. |..||     :||..|.|.....:.....|..
  Fly    69 GGVHIAWSIGFDSSL---------SELEVTNHVQICWF-----IGAIIGALLGGFFSRWFPYKTL 119

Human   112 IMFSAVPSAAGYALMA-GAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRG----ALGA 171
            :.|.::.:..|..:|| ....|..||.||.:.|.|.||..|.......|::....||    |...
  Fly   120 MEFCSLITITGGIVMAVNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQ 184

Human   172 TPQLMAVFGSLSLYALGLLLPWRW---------------LAVAGEAPVLIMILLLSFMPNSPRFL 221
            .|..:.:|       :.::....|               ..|.|.. .|::..|||.  .||..|
  Fly   185 WPTTIGIF-------VQIVCSHSWDVQSDFTEEQFQGVLSGVLGSI-ALLLAFLLSI--ESPVDL 239

Human   222 LSRGRDEEALRALAWLRGTDVDVHWEFEQIQDN---VRRQSSRVSWAEARAPHVCRPITVAL-LM 282
            |.:|.::.|::||:.|:.........::|::|:   |....| :.|..|      .|..|.| ::
  Fly   240 LEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRS-MGWRHA------LPALVRLSVL 297

Human   283 RLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAA 347
            |.|..|:  ..::|.....:.||.|.........:.|.:||:.....:..:|..|||:
  Fly   298 RALYALS--LSVMVAFTLAWTSTEVYGDSSGPYVLFGFLRLMGSFTTSFALDSLGRKI------- 353

Human   348 IMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVG 412
                 .|.|||.|       |.....||.|...|  :.||......:.|..||...||.   .:.
  Fly   354 -----PLLLGLVI-------SGCLACGLASRFAG--SHPLTFSGNRMALWLLLIYQLFA---GIA 401

Human   413 WGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFF--AAICLVS 475
            :.|.:..| ||..|.|.:.....:..:...:...:|.:.....:.:....|..:||  ..:.|..
  Fly   402 FAPSSSYL-SEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAAIGSDSSYVALYFFILGGLLLAG 465

Human   476 LVFTGCCVPETKGRSLEQIESFFR 499
            .:|:...:||||..:|.|.:..|:
  Fly   466 FLFSVWYMPETKDTTLLQAQFKFQ 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		5/27 (19%)
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	106/480 (22%)
CG32053	NP_729587.1	MFS	95..481	CDD:475125	99/434 (23%)