Protein Alignment SLC2A6 and CG15408

DIOPT Version :10

• Sequence 1: NP_060055.2
• Gene: SLC2A6 / 11182
• HGNCID: 11011
• Length: 507
• Species: Homo sapiens
• Sequence 2: NP_608767.1
• Gene: CG15408 / 33548
• FlyBaseID: FBgn0031523
• Length: 466
• Species: Drosophila melanogaster
• Alignment Length: 488
• Identity: 115/488 - (23%)
• Similarity: 212/488 - (43%)
• Gaps: 70/488 - (14%)

Human    34 QNKRVFLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKS--QASWFGSVFTLGAAAGG 96
            :|:...|.|....:.:.|.|..:.:.||.:..|: |..|.....||  :.||.||:..:|:..|.
  Fly    16 RNRYQLLTTLLINVISISHGIGIGWLSPTLRKLQ-SDSPAGFEVKSEFEISWVGSMLGMGSVTGN 79

Human    97 LSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIA 161
            :....|...||.|..::..|:|.:..:.|:..|..:..|.:||.|.|..||......|:.:||||
  Fly    80 ILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPILLSEIA 144

Human   162 PPGVRGALGATPQLMAVFGSLSLYALGLLLPWRWLAVAGEAPVLIMIL-------LLSFMPNSPR 219
            ...:||...|...|....|.|..|.:|..||:.      ..|::::||       :|.|:..||.
  Fly   145 DANIRGTFSAMVMLSVNVGILVGYIIGTHLPYY------SIPLMVLILPLWYLISVLLFIKESPM 203

Human   220 FLLSRGRDEEALRALAW---LRGTDVDVH------WEFE----------QIQDNVRRQS--SRVS 263
            .|:..|:...|.|:..:   ::.:| ::|      .|||          .:||.|..:.  ||.:
  Fly   204 HLIRIGKYSAAERSFRYYKNIKDSD-NIHDQNRAMEEFEIMKIALTKGDALQDAVTFKDFYSRPA 267

Human   264 WAEARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAIVGAVRLLSVLI 328
             .:|..|        ||::.:..|.:|:..::.|:..||.::...:.|.....|:|||::|...:
  Fly   268 -LKAYGP--------ALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILGTYV 323

Human   329 AALTMDLAGRKVLLFVSAAIMFAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGY 393
            ..|..|:.|||:|:.||...:..:....|.:..:.            ||.:.|:
  Fly   324 TTLLCDICGRKLLMLVSTGGVAISLTAFGFFTKYA------------ESHNIGE----------- 365

Human   394 LTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVST 458
            .:.:|||...:.|....:|.....::.:.|:.|::.|..|:.:.::...:..|::...|...:..
  Fly   366 YSWIPLLLMSMDIFLGNIGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQ 430

Human   459 FGLQVPFFFFAAICLVSLVFTGCCVPETKGRSL 491
            :|:....:..|.:..:|.::....:.||||:|:
  Fly   431 WGISATMWSCAGVTALSSLYFTYFMKETKGKSM 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A6	NP_060055.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		Dileucine internalization motif. /evidence=ECO:0000255	5..6
		MFS_GLUT6_Class3	39..493	CDD:340992	114/483 (24%)
CG15408	NP_608767.1	MFS_GLUT6_8_Class3_like	21..465	CDD:340916	114/483 (24%)