back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHIT1 and Cht7

DIOPT Version :9

Sequence 1:	NP_003456.1	Gene:	CHIT1 / 1118	HGNCID:	1936	Length:	466	Species:	Homo sapiens
Sequence 2:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	197/372 - (52%)
Similarity:	249/372 - (66%)	Gaps:	13/372 - (3%)

- Green bases have known domain annotations that are detailed below.

Human    23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDET------LYQEFN 81
            |:|||:|||:|||....:|:|:|:...||||:|:||..:..::||:.|.||||      ||:...
  Fly   124 KIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMM 188

Human    82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQG 146
            .|||.|||||.|||:|||:||||||.||.:|...|||||.|||.||||..|||||:|||||  :|
  Fly   189 TLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYP--KG 251

Human   147 SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMA 211
            |.  ||:.|..|:::|..||:.|||...|.|||||||||.|...:..||:|..||..|||:||||
  Fly   252 SD--DKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMA 314

Human   212 YDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASS 276
            |||||.||:.||||:|||....:|.....|:||.|...|::.|.|..||::||||||||||||:.
  Fly   315 YDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANP 379

Human   277 SDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQKVPYIFRDNQWVGFDDVES 339
            ......|||:|.|..|.:|||||.|||||:|..  .||......:.||||:...:|||||||..:
  Fly   380 DKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERA 444

Human   340 FKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-RYPLIQTLRQEL 385
            .:.|:.::|..|.||||||.:|:|||.|..|... :||||..:|:||
  Fly   445 IRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREEL 491

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.