Protein Alignment SOX21 and SoxN

DIOPT Version :9

• Sequence 1: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Sequence 2: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 328
• Identity: 131/328 - (39%)
• Similarity: 147/328 - (44%)
• Gaps: 120/328 - (36%)

Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70
            |.|||||||||||||.||||||.:|||||||||||||||:||.|:||||||||||||||||:|||
  Fly   177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMK 241

Human    71 EHPDYKYRPRRKPKTLLK-KDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVP------- 127
            ||||||||||||.|||.| |:|      |.:||:.    |....|.|   ..|..:.|
  Fly   242 EHPDYKYRPRRKTKTLTKTKEK------YPMGGLM----PGQTVGGG---APGEPVTPTRVQGQP 293

Human   128 ---ESLLANPEKAAAAAAAAAARV---------------FFPQSAAAAAAAAAAAAAGSPY---- 170
               :||..:...||||||||||..               :.|......|..|.|||..:.|
  Fly   294 GQNQSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQH 358

Human   171 ---------SLLDLGSKMAEISSSSSGLPYASSL------------------GYPT--AGAGAFH 206
                     .:.:.|..|.:..|.....||.|||                  |.||  .|.|...
  Fly   359 YAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGSPSPYGGSSLQQQPGSPTPYGGGGGGG 423

Human   207 G------------------------------------------------AAAAAAAAAAAAGGHT 223
            |                                                ||||||||||||||..
  Fly   424 GQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAAAAAAAAAGGGE 488

Human   224 HSH 226
            .:|
  Fly   489 LNH 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX21	NP_009015.1	SOX-TCF_HMG-box	7..78	CDD:238684	62/70 (89%)
		SOXp	77..>95	CDD:403523	12/18 (67%)
SoxN	NP_001260269.1	SOX-TCF_HMG-box	178..249	CDD:238684	62/70 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.910