Protein Alignment SOX21 and D

DIOPT Version :10

• Sequence 1: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Sequence 2: NP_524066.1
• Gene: D / 39570
• FlyBaseID: FBgn0000411
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 118/274 - (43%)
• Similarity: 143/274 - (52%)
• Gaps: 64/274 - (23%)

Human     7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKE 71
            |:||||||||||||.|||::|::||||||||||||||||||||.||||||||||||||||:||||
  Fly   141 HIKRPMNAFMVWSRLQRRQIAKDNPKMHNSEISKRLGAEWKLLAESEKRPFIDEAKRLRALHMKE 205

Human    72 HPDYKYRPRRKPKTLLKKDKFAFPVPYG-----LGGVADAEHPALKAGAGLHAGAGGGLVPESLL 131
            |||||||||||||..|...      |.|     .||:...     |.|||..|||||
  Fly   206 HPDYKYRPRRKPKNPLTAG------PQGGLQMQAGGMGQQ-----KLGAGPGAGAGG-------- 251

Human   132 ANPEKAAAAAAAAAARV-----------FFP-------QSAAAAAAAAAAAAAGSPYSLLDLGSK 178
            .||........|.:..:           |.|       ||.||||||              :.::
  Fly   252 YNPFHQLPPYFAPSHHLDQGYPVPYFGGFDPLALSKLHQSQAAAAAA--------------VNNQ 302

Human   179 MAEISSSSSGLPYASSLGYPTAGAGAFHGAAAA---AAAAAAAAGGH-THSHPSPG-NPGYMIPC 238
            ..:...:...||..|...:   .:|.:.|.:|.   ||.:|.|||.: :.|..||| :||.:.|.
  Fly   303 GQQQGQAPPQLPPTSLSSF---YSGIYSGISAPSLYAAHSANAAGLYPSSSTSSPGSSPGTITPN 364

Human   239 NCSAWPSPGLQPPL 252
            .........|:.|:
  Fly   365 GMDGSMDSALRRPV 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX21	NP_009015.1	HMG-box_SoxB	6..85	CDD:438790	69/77 (90%)
		SOXp	77..>95	CDD:463537	9/17 (53%)
D	NP_524066.1	HMG-box_SoxB	140..219	CDD:438790	69/77 (90%)