Protein Alignment SOX21 and Sox21a

DIOPT Version :10

• Sequence 1: NP_009015.1
• Gene: SOX21 / 11166
• HGNCID: 11197
• Length: 276
• Species: Homo sapiens
• Sequence 2: NP_001261827.1
• Gene: Sox21a / 39567
• FlyBaseID: FBgn0036411
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 116/290 - (40%)
• Similarity: 133/290 - (45%)
• Gaps: 92/290 - (31%)

Human     6 DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMK 70
            ||:||||||||||||.|||||||:||||||||||||||||||||||.:|||||||||||||:|||
  Fly   119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMK 183

Human    71 EHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPE 135
            ||||||||||||||||.|.     |||.|.||           |.|  .||.||:
  Fly   184 EHPDYKYRPRRKPKTLNKS-----PVPGGGGG-----------GGG--GGANGGV---------- 220

Human   136 KAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPY----SLLDLGSKMAEISSSSSGLPYASSLG 196
                           ....|..:..:...:.|||.    .|..||..:..:.......||.|
  Fly   221 ---------------NAGGAGNSGPSGPGSVGSPKDMQPQLSPLGQSLPHLHGHPHQSPYQS--- 267

Human   197 YPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYIL----- 256
                                     |.| ||.| :|.::.....:.....|...||...|
  Fly   268 -------------------------HPH-HPHP-HPHHVQLAAATLSAKYGFGSPLELSLPRLPN 305

Human   257 -LPGMGKPQLDP---------YPAAYAAAL 276
             .||:....|||         ..|.||.::
  Fly   306 AFPGLAHYPLDPTLALDLQARLQAMYAGSI 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOX21	NP_009015.1	HMG-box_SoxB	6..85	CDD:438790	72/78 (92%)
		SOXp	77..>95	CDD:463537	11/17 (65%)
Sox21a	NP_001261827.1	HMG-box_SoxB	119..198	CDD:438790	72/78 (92%)