DRSC/TRiP Functional Genomics Resources

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Protein Alignment SOX21 and Sox15

DIOPT Version :9

Sequence 1:NP_009015.1 Gene:SOX21 / 11166 HGNCID:11197 Length:276 Species:Homo sapiens
Sequence 2:NP_523739.2 Gene:Sox15 / 36575 FlyBaseID:FBgn0005613 Length:784 Species:Drosophila melanogaster


Alignment Length:229 Identity:72/229 - (31%)
Similarity:116/229 - (50%) Gaps:30/229 - (13%)


- Green bases have known domain annotations that are detailed below.


Human     8 VKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEH 72
            ::|||||||||::.:|:|:|.|||.:||:::||.||.:|:.||..::||:::||:|||.:||.||
  Fly   215 IRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEH 279

Human    73 PDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKA 137
            |:|||||||:     |:.|.....|   ||...:|       :..:.|.||.      .:||:.|
  Fly   280 PNYKYRPRRR-----KQSKLRAMQP---GGKEQSE-------SSPNPGTGGS------KSNPKLA 323

Human   138 AAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGA 202
            ....|.|::....|...:...:........:|..|.:  ..:....|.||...|:::.......:
  Fly   324 TPPLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYE--QPLKPTYSPSSVDCYSNADSTEQIES 386

Human   203 GAFHGAAAAAAAAAAAAGGHTHS-------HPSP 229
            .|.:...|....::...||:.:|       .|||
  Fly   387 LAANCPPALLNESSPTGGGYDNSLLLKKLTKPSP 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SOX21NP_009015.1 SOX-TCF_HMG-box 7..78 CDD:238684 38/69 (55%)
SOXp 77..>95 CDD:403523 7/17 (41%)
Sox15NP_523739.2 SOX-TCF_HMG-box 214..285 CDD:238684 38/69 (55%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R685
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.940

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