Protein Alignment NUDT6 and CG8128

DIOPT Version :10

• Sequence 1: NP_009014.2
• Gene: NUDT6 / 11162
• HGNCID: 8053
• Length: 316
• Species: Homo sapiens
• Sequence 2: NP_573053.2
• Gene: CG8128 / 32504
• FlyBaseID: FBgn0030668
• Length: 330
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 95/274 - (34%)
• Similarity: 144/274 - (52%)
• Gaps: 20/274 - (7%)

Human    47 QGELDRFGGISVRLARLDAL-DRLDAAAFQKGLQAAVQQWRSEGRTAVWLHIPILQSRFIAPAAS 110
            :|..|||.|::|     |.. :.:|.::|:..|..::..|.:....|:|..:...|:.::...|.
  Fly    68 RGITDRFAGVTV-----DGREENVDKSSFRDKLTKSLDFWTTNKNRAIWFRVYKEQADWVPILAE 127

Human   111 LGFCFHHAESDSSTLTLWLRE-GPSRLPGYASHQVGVAGAVFDESTRKILVVQDR-NKLKNMWKF 173
            .||.||||::....:..||.| ..|.||.||...:||.|.|.:|.. ::|||.|| ..:.|.||.
  Fly   128 NGFDFHHAKTGVVVMYRWLPEHESSNLPTYAHTLMGVGGLVINEQD-EVLVVSDRFAMIPNSWKL 191

Human   174 PGGLSEPEEDIGDTAVREVFEETGIKSEFRSVLSIRQQHTNPGAFGKSDMYIICRLKPYSFTINF 238
            |||..||.|::.|.|:|||.|||||::|||||:|:|  |.:.|.||.||||::..|||.:.....
  Fly   192 PGGYVEPRENLIDAAIREVAEETGIRTEFRSVVSLR--HAHGGTFGCSDMYVVIALKPLNLDFTR 254

Human   239 CQEECLRCEWMDLNDLAKTENTTPITSRVARLLLYGYREGFDKIDLTVEELPAVYTGL--FYKLY 301
            |:.|..|.:||.:.:..|    .|......|..:..:.: :.|..||:.....|:..|  .|.||
  Fly   255 CEREIARIQWMPIAEYLK----HPQVHETNRQFVCTFLD-YQKRGLTLTCRDEVHQVLKKKYNLY 314

Human   302 H--KELPENYKTMK 313
            :  :|.|:..:..|
  Fly   315 YVDREQPQEQQDKK 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUDT6	NP_009014.2	Nudix_hydro	46..129	CDD:465697	21/82 (26%)
		NUDIX_ASFGF2_Nudt6	142..273	CDD:467554	55/131 (42%)
		Nudix box	176..197		11/20 (55%)
CG8128	NP_573053.2	Nudix_hydro	67..146	CDD:465697	21/82 (26%)
		NUDIX_ASFGF2_Nudt6	159..290	CDD:467554	55/138 (40%)