Protein Alignment LDB3 and ldb3

DIOPT Version :10

• Sequence 1: NP_001165081.1
• Gene: LDB3 / 11155
• HGNCID: 15710
• Length: 732
• Species: Homo sapiens
• Sequence 2: XP_017950805.1
• Gene: ldb3 / 394699
• XenbaseID: XB-GENE-922381
• Length: 818
• Species: Xenopus tropicalis
• Alignment Length: 893
• Identity: 443/893 - (49%)
• Similarity: 517/893 - (57%)
• Gaps: 236/893 - (26%)

Human     1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEA 65
            |:|:|:|:|||||||||||||||||||||||:|||||||||.::||||||||||||||.||||||
 Frog     1 MAYNVSLSGPGPWGFRLQGGKDFNMPLTISRVTPGSKAAQSSVNQGDLVVAIDGVNTDGMTHLEA 65

Human    66 QNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASP 130
            |||||||||||.|||||||||.|:.|..|.:.:|:||||||||.||:.|||..|.|......|.|
 Frog    66 QNKIKSASYNLGLTLQKSKRPGPVPTATPRMDSPMPVIPHQKDHALEINGSRTAYSTVSSKSAVP 130

Human   131 ------------GTPGTPELRPTFSPAFSRPSAFSSLAE---ASDPGPPRASLRAKTSP--EGAR 178
                        |.....|...:.|..|.:.|..:|::.   |||..|.:.|:.:|..|  .||.
 Frog   131 LVGSMSTNETMAGYVSKQETNHSHSSTFIKTSVRTSMSTHSVASDASPIKGSIGSKVDPLVSGAN 195

Human   179 DLLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGADYQERFNPSALK 243
            :   |......|:.|.||||:||||||||.|||:|:::||:|:||..||
 Frog   196 N---PINQFSPSKNRLYNNPVGLYSAETLNEMAEMHKLSLKGRASEGGL---------------- 241

Human   244 DSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLAVD 308
                  |:                                              |:||:||..||
 Frog   242 ------HR----------------------------------------------GNLPVKDPLVD 254

Human   309 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR------ 367
            .||||||||:|:|.|.|.|.|:||||::||||:|||:||.:||||:||||||:||||:.
 Frog   255 IASPVYQAVLKNQGKTESEIDDWARRAANLQSKSFRVLAHITGTEYMQDPDEDALRRASSKENVA 319

Human   368 -------------PQASS-------------------------YSPAVAASSAPA--THTS---- 388
                         |.|.|                         ||......|.|.  .|||
 Frog   320 KSPEISPAGAKVLPSARSGTWHPTKSPTREDIPSQPSPVSSRGYSVRFGGDSVPRKNVHTSTDQN 384

Human   389 -----------YSEGPAAPA----------PKPRVVTTASIRPSV---------------YQ--- 414
                       |...|||.:          .|...:..::|..::               ||
 Frog   385 LPKLSPPITSTYKRAPAAASISASQKTFQGSKNMSIAASTISSAISAQSSHQQQSSFTTTYQSKA 449

Human   415 ------------PVPASTYS--------------------PSPGANYS------PTPYTPSPAPA 441
                        |||...||                    |.|...||      |.||.....||
 Frog   450 SQSFSSSTTAKGPVPYGAYSEPAAKGPVPYGGYSEPAAKGPVPYGGYSEPAAKGPVPYGGYSEPA 514

Human   442 YTPSP-APAYTPSPVPTYTPSPAPAYTPSPAPNYNPA--PSVAYSGGPAEPASRPPWVTDDSFSQ 503
            .:.:| |||..|..|.|.:..|: .|.||.||...|.  |:..|:....||::||||||||:|||
 Frog   515 ASSAPAAPAPKPRVVTTASIKPS-VYQPSQAPAPGPVQPPAQIYAPPTQEPSNRPPWVTDDNFSQ 578

Human   504 KFAPGKSTTSISKQTLPR---------GGPAYTP-----AGPQVPPLARGTVQRAERFPASSRTP 554
            ||||||||::::||.||:         ..|:|||     :..|||   ||.:|||||||||||||
 Frog   579 KFAPGKSTSTVTKQILPKAAPLPPTPISAPSYTPQPVGQSPSQVP---RGLIQRAERFPASSRTP 640

Human   555 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCN 619
            ||..||::||||||||||||||||||.||:||||||||.|||||..|||||||||||||.||:||
 Frog   641 LCASCNSIIRGPFLVAMGRSWHPEEFNCAHCKTSLADVSFVEEQKGVYCERCYEQFFAPTCARCN 705

Human   620 TKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAG 684
            |||||||||||||||||||||||||:|||||||||||||||||||||:.||||||||||||||||
 Frog   706 TKIMGEVMHALRQTWHTTCFVCAACRKPFGNSLFHMEDGEPYCEKDYVALFSTKCHGCDFPVEAG 770

Human   685 DKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTINL 732
            |||||||||||||||||||||||||||||||||||:||||||||.||:
 Frog   771 DKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKKHAHAINV 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LDB3	NP_001165081.1	PDZ_PDLIM-like	4..82	CDD:467235	68/77 (88%)
		ZM	189..214	CDD:128974	17/24 (71%)
		DUF4749	263..365	CDD:464948	46/101 (46%)
		PHA03247	<387..554	CDD:223021	85/264 (32%)
		LIM1_ZASP_Cypher	556..607	CDD:188838	41/50 (82%)
		LIM2_Enigma_like	615..666	CDD:188748	48/50 (96%)
		LIM3_Enigma_like	674..727	CDD:188749	51/52 (98%)
ldb3	XP_017950805.1	PDZ_PDLIM-like	4..82	CDD:467235	68/77 (88%)
		DUF4749	209..311	CDD:464948	70/169 (41%)
		MISS	<462..625	CDD:318115	62/166 (37%)
		LIM1_ZASP_Cypher	642..693	CDD:188838	41/50 (82%)
		LIM2_Enigma_like	701..752	CDD:188748	48/50 (96%)
		LIM3_Enigma_like	760..813	CDD:188749	51/52 (98%)