DRSC/TRiP Functional Genomics Resources

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Protein Alignment WDR45 and Wdr45

DIOPT Version :10

Sequence 1:NP_009006.2 Gene:WDR45 / 11152 HGNCID:28912 Length:361 Species:Homo sapiens
Sequence 2:XP_006256772.1 Gene:Wdr45 / 302559 RGDID:1359718 Length:361 Species:Rattus norvegicus


Alignment Length:361 Identity:355/361 - (98%)
Similarity:360/361 - (99%) Gaps:0/361 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLAL 65
            ||||||||||||.|||||||||||||||||||||||||||||||||||||:||||||||||||||
  Rat     1 MTQQPLRGVTSLHFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSVGLVEMLHRSNLLAL 65

Human    66 VGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFP 130
            ||||||||||||||||||||||||||||:|||||||||||||:||||||||||||:|||||||||
  Rat    66 VGGGSSPKFSEISAVLIWDDAREGKDSKDKLVLEFTFTKPVLAVRMRHDKIVIVLRNRIYVYSFP 130

Human   131 DNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTINAHQSD 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 DNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFTINAHQSD 195

Human   196 IACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKG 260
            :||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 VACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSHDSSFLCASSDKG 260

Human   261 TVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVI 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 TVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESACICAFGRNTSKNVNSVI 325

Human   326 AICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF 361
            ||||||||||||||||||||||||||||||||||||
  Rat   326 AICVDGTFHKYVFTPDGNCNREAFDVYLDICDDDDF 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WDR45NP_009006.2 WD 1 1..34 31/32 (97%)
WD40 8..265 CDD:475233 250/256 (98%)
WD 3 93..129 32/35 (91%)
WD 4 134..175 40/40 (100%)
WD40 <168..>275 CDD:441893 105/106 (99%)
WD 5 184..223 37/38 (97%)
WD40 repeat 197..233 CDD:293791 35/35 (100%)
WD 6 228..267 38/38 (100%)
L/FRRG motif. /evidence=ECO:0000250|UniProtKB:Q9Y4P8 232..235 2/2 (100%)
WD 7 285..330 44/44 (100%)
Wdr45XP_006256772.1 WD40 8..265 CDD:475233 250/256 (98%)
WD40 <168..>272 CDD:441893 102/103 (99%)
WD40 repeat 197..233 CDD:293791 35/35 (100%)

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