Protein Alignment POPDC1 and bves

DIOPT Version :10

• Sequence 1: NP_009004.2
• Gene: POPDC1 / 11149
• HGNCID: 1152
• Length: 360
• Species: Homo sapiens
• Sequence 2: NP_608426.1
• Gene: bves / 33083
• FlyBaseID: FBgn0031150
• Length: 414
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 84/277 - (30%)
• Similarity: 140/277 - (50%)
• Gaps: 46/277 - (16%)

Human    41 HHLVFHVANICFAVGLVIPTTLHLH----MIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFL 101
            |||.|.:......:..:.|     |    .:::|.||.:||.:..:...|...|.|:::|:.:.|
  Fly    99 HHLYFQLGWAFLFLAFLAP-----HGPYGALWMRAMLLIGCLMMGMHGYLVAFAPDVILWSGMGL 158

Human   102 GVNILHLSYLLYKKRPVKIEKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDK 166
            .||.::|..:|.:.|||:.|:|:..:|..||:||.|....|:::.....:|:.||..:.||.|..
  Fly   159 FVNFIYLVVVLCRLRPVRFEQEIEAVYLALFQPLHVTRHQFKKVLNCMKVIRALKYQEVYAQEKV 223

Human   167 TSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWS 231
            |.||. ||::|.||:.||.....||.::|..|:||||:..  :...:.|||:|:|.:..|.|.|.
  Fly   224 TKVDS-LSLVLSGKLVVSQHQRALHIVFPHQFLDSPEWFG--VSTDDYFQVSIMAMEESRVLIWH 285

Human   232 RERLTYFLESEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSI 296
            |::|...:.:||||..:|.:::|:|:..||..:                    ||:|     .||
  Fly   286 RDKLKLSIMAEPFLQTVFDHILGRDVVKKLMQV--------------------TQVS-----ESI 325

Human   297 AS---------SSDSDD 304
            ||         :.|::|
  Fly   326 ASNGFLPSGGYAEDAED 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POPDC1	NP_009004.2	Popeye	41..266	CDD:461448	75/228 (33%)
		Required for interaction with CAV3. /evidence=ECO:0000250|UniProtKB:Q9ES83	93..115		6/21 (29%)
		Required for interaction with KCNK2. /evidence=ECO:0000269|PubMed:26642364	136..186		18/49 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	317..360
bves	NP_608426.1	Popeye	98..320	CDD:461448	75/248 (30%)