DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SLC7A9 and CG1607

DIOPT Version :9

Sequence 1:	NP_001119807.1	Gene:	SLC7A9 / 11136	HGNCID:	11067	Length:	487	Species:	Homo sapiens
Sequence 2:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	192/464 - (41%)
Similarity:	298/464 - (64%)	Gaps:	5/464 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    25 SLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAVGPCLIIWAACGVLATLGALCFAELGTM 89
            :|:.::.|::|.::|||:||||||||||..||..|.:|...||:|...|:.:.:||.|:||||||
  Fly    44 TLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAYCYAELGTM 108

Human    90 ITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKPTSFAIICLSFSEYVCAPFYVGCKPPQIVVKCL 154
            |||||.:|.|:||.:||..|::..|...::::|.|.||:.|:||.||..||:..|.||:...:.|
  Fly   109 ITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPECTPPEDSARLL 173

Human   155 AAAAILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVG 219
            |...||.::.:|...|:..:.||:|||.|||:.:.|||.:|:..|..|||:.|  :||.....|.
  Fly   174 AVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYF--TFENTDTKVT 236

Human   220 AISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELL 284
            :|:|:||:||:||:|||.||:|.|||::|.:|||.||.|...|||..|::.|||::|:::..|::
  Fly   237 SIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVM 301

Human   285 QSQAVAVTFGDRVLYPASWIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRL 349
            .|.|||||:.:|.....:|.:|:|||.||.||.||...|:.||.|.....|.|.::|:.|.::|.
  Fly   302 GSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMPEILTMIQIQRF 366

Human   350 TPAPAIIFYGIIATIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIP 414
            ||.||::...:::.:|:...||.:|:||..||.||..|:.:|.|..:|:.:..|.|||:||:|.|
  Fly   367 TPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNLPRPIRVPMVFP 431

Human   415 VLMTLISVFLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVHYKFG--WAQKISKPITMHLQMLM 477
            ::..:.::|:.:.|:.:.|. |..|.:|.|||.:..|.:|:.:|..  |.||....:|..||.::
  Fly   432 IVYLIATIFVTVVPMYASPV-ETGYGILMILSSIPVYLVFIAWKNKPIWFQKTMVSLTRFLQKML 495

Human   478 EVVPPEEDP 486
            .|:..:..|
  Fly   496 MVLGKQTKP 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A9	NP_001119807.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
SLC7A9	NP_001119807.1	2A0308	26..484	CDD:273332	191/459 (42%)
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	191/459 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.680