Protein Alignment PTPRT and PTP1

DIOPT Version :9

• Sequence 1: XP_024307588.1
• Gene: PTPRT / 11122
• HGNCID: 9682
• Length: 1535
• Species: Homo sapiens
• Sequence 2: NP_010051.1
• Gene: PTP1 / 851368
• SGDID: S000002389
• Length: 335
• Species: Saccharomyces cerevisiae
• Alignment Length: 360
• Identity: 94/360 - (26%)
• Similarity: 137/360 - (38%)
• Gaps: 140/360 - (38%)

Human   923 WDTAKEDENRN--KNRYGNIISCRGRSPAKRADMRKTPQLDKEMSSVFPEAPLIQRRTLAATWDD 985
            |......|.||  :|||.||:      |.:|
Yeast    42 WSLGVSIEPRNDARNRYVNIM------PYER---------------------------------- 66

Human   986 HSRVRLLVLDGDPHSDYINANY----IDGYH-RPRHYIATQGPMQETVKDFWRMIWQE---NSAS 1042
             :||.|..|.|   :|||||:|    :.|.. .|.:|||||||.::|...||:|.:..   ::..
Yeast    67 -NRVHLKTLSG---NDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIV 127

Human  1043 IVMVTNLVEVGRHPAEHTVGNATLGRAASPGMVKCVRYWP---------------------DDTE 1086
            |||||.|||..|.                    ||.:|||                     |.|:
Yeast   128 IVMVTPLVEYNRE--------------------KCYQYWPRGGVDDTVRIASKWESPGGANDMTQ 172

Human  1087 VYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRL---------------FHFTSWPDHGVP 1136
            ...|:|:..:....:            |.|:.:.:::|               |:|..|.|...|
Yeast   173 FPSDLKIEFVNVHKV------------KDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKP 225

Human  1137 CYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTML----------------DMAE 1185
            .....::........|| ....||:||||||.||||.|||:|.::                |.|.
Yeast   226 EEVVPIMELCAHSHSLN-SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRAT 289

Human  1186 NEGVVDIF-NCVRELRAQRVNLVQTEEQYVFVHDA 1219
            .|...|:. ..|.:||:||:.:|||::|::|::.|
Yeast   290 EEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHA 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PTPRT	XP_024307588.1	MAM	29..189	CDD:214533
		fn3	294..360	CDD:306538
		FN3	390..480	CDD:238020
		fn3	502..577	CDD:306538
		PTPc	985..1222	CDD:238006	83/296 (28%)
		PTPc	1284..1504	CDD:238006
PTP1	NP_010051.1	COG5599	1..335	CDD:227886	94/360 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	129	1.000	Domainoid score	I1294
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910