DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTN3A1 and DIP-theta

DIOPT Version :9

Sequence 1:	NP_008979.3	Gene:	BTN3A1 / 11119	HGNCID:	1138	Length:	513	Species:	Homo sapiens
Sequence 2:	NP_723103.1	Gene:	DIP-theta / 33795	FlyBaseID:	FBgn0051646	Length:	606	Species:	Drosophila melanogaster

Alignment Length:	245	Identity:	53/245 - (21%)
Similarity:	93/245 - (37%)	Gaps:	64/245 - (26%)

- Green bases have known domain annotations that are detailed below.

Human    44 VGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGK 108
            |..:|.|.|   ...:.:|.::.|:....:.::.:.........|.|..:            |.|
  Fly   143 VSREAVLQC---VVDNLQTYKIAWLRVDTQTILTIQNHVITKNHRMSITH------------AEK 192

Human   109 AA--LRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGY--------KDG-GI 162
            .|  |||.:|..||.|.|:|......      ::.:|..|...:..|:..|        ::| .:
  Fly   193 RAWILRIRDVKESDKGWYMCQINTDP------MKSQVGYLDVVVPPDILDYPTSTDMVIREGSNV 251

Human   163 HLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGV---GLYAVAASV--IMRGS----SGEGV 218
            .|:|.:|| .|.|.|.|....||.||   .|..|:.|   |.:...|.|  :..|:    :..|:
  Fly   252 TLKCAATG-SPTPTITWRREGGELIP---LPNGAEAVAYNGSFLTIAKVNRLNMGAYLCIASNGI 312

Human   219 SCT----------------IRSSLLGLEKTASISI---ADPFFRSAQRWI 249
            ..|                |::.|:|...|.:|::   ::.:.:|...|:
  Fly   313 PPTVSKRVMLIVHFPPMIWIQNQLVGAALTQNITLECQSEAYPKSINYWM 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTN3A1	NP_008979.3	IG_like	37..143	CDD:214653	20/100 (20%)
		Ig_MOG_like	45..144	CDD:143190	19/100 (19%)
		SPRY_PRY_BTN3	337..512	CDD:293992
DIP-theta	NP_723103.1	Ig	137..230	CDD:299845	22/107 (21%)
		IG_like	137..230	CDD:214653	22/107 (21%)
		IG_like	240..324	CDD:214653	22/87 (25%)
		IGc2	247..310	CDD:197706	20/66 (30%)
		Ig	327..419	CDD:299845	7/36 (19%)
		IG_like	343..420	CDD:214653	3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910