DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BTN3A2 and RGD1624210

DIOPT Version :9

Sequence 1:	XP_006715042.1	Gene:	BTN3A2 / 11118	HGNCID:	1139	Length:	339	Species:	Homo sapiens
Sequence 2:	XP_038954996.1	Gene:	RGD1624210 / 686977	RGDID:	1624210	Length:	548	Species:	Rattus norvegicus

Alignment Length:	325	Identity:	126/325 - (38%)
Similarity:	187/325 - (57%)	Gaps:	20/325 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     9 FLLLNFHVSLLLVQLLTPCSA---QFSVLGPSGPILAMVGEDADLPCHLFPTMSAETM-ELKWVS 69
            |.:.:.|..:.| |.||..|.   .|.|.|||.||:|.:|.:|.|||.:||.||.|.| ||:|..
  Rat    17 FRVCSVHCPVSL-QPLTATSVSTEDFLVFGPSDPIVATLGGEAILPCSVFPVMSVENMEELRWFR 80

Human    70 SSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFY 134
            :...:.|.||.|.:|.::.|...|..|||:::|....||||:||.||..||||.|:|:|:.|.|:
  Rat    81 TRFSEAVFVYRDQEEQKEGQLPGYSQRTSLVKDQFHEGKAAVRIQNVQESDSGIYVCHFKQGHFH 145

Human   135 EKALVELKVAALGSNLHVEVKGYEDGGIHLECRSTGWYPQPQIQWSNAKGENIPAVEAPVVADGV 199
            |:|::||||||:||...|.:||.|:||:.:.|.::||||:||:.|.:::||::||....:..|..
  Rat   146 EEAILELKVAAMGSVPEVYIKGPEEGGVCVVCMTSGWYPEPQVHWRDSRGEDLPASSETLHEDAE 210

Human   200 GLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIAALPFADPFFRSAQPWIAALAGTLPIL 264
            ||:....|:::|..|...|:|...|.:||.||.     .|:...:|||..|.||.|.::..|.::
  Rat   211 GLFSTETSLVLRDSSVRNVTCSTFNPILGQEKA-----MAMVIPEPFFPQASPWKADISEILKMM 270

Human   265 LLLLAGASYFLWRQQKEITALS---SEIESEQEMKEMGYAATEREISLR--ESLQEELKRKKIQY 324
            .:||...|..|.|.......|.   |..:.|::..:|     .:|.:||  .:|:|||.|:|..|
  Rat   271 QVLLLLTSCLLMRAHSARLRLQWKWSHFQLEKDESQM-----TKEDALRTASALREELDRRKAAY 330

Human 325 324
Rat 331 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTN3A2	XP_006715042.1	IG_like	37..143	CDD:214653	50/106 (47%)
		Ig_MOG_like	45..144	CDD:143190	47/99 (47%)
		MYO10_CC	277..330	CDD:293340	15/53 (28%)
RGD1624210	XP_038954996.1	IgV_MOG_like	41..155	CDD:409378	55/113 (49%)
		Ig strand B	58..62	CDD:409378	2/3 (67%)
		Ig strand C	74..79	CDD:409378	2/4 (50%)
		Ig strand E	120..124	CDD:409378	2/3 (67%)
		Ig strand F	134..139	CDD:409378	2/4 (50%)
		Ig strand G	147..150	CDD:409378	1/2 (50%)
		Ig	158..242	CDD:416386	31/83 (37%)
		SPRY_PRY_C-I_1	353..506	CDD:293968
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	137	1.000	Domainoid score	I34658
eggNOG	1	0.900	-	-		E1_28KB3
HGNC	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D186278at7742
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820