DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CIT and DBF20

DIOPT Version :9

Sequence 1:XP_011536085.1 Gene:CIT / 11113 HGNCID:1985 Length:2084 Species:Homo sapiens
Sequence 2:NP_015436.1 Gene:DBF20 / 856227 SGDID:S000006315 Length:564 Species:Saccharomyces cerevisiae


Alignment Length:439 Identity:133/439 - (30%)
Similarity:218/439 - (49%) Gaps:95/439 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    70 IKHVSNFV----------RKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYA 124
            :|:|||.|          |::.  :...:.|:|..|||::.:.||.|.:.:|.:.::|.:.:|.|
Yeast   134 VKNVSNKVLNEEWALYLQREHE--VLRKRRLKPKHKDFQILTQVGQGGYGQVYLAKKKDSDEICA 196

Human   125 MKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLL--N 187
            :|::.||.|....:.:....||:||:.:.|.|:.:|.|||||...|||.||:.||||..:||  .
Yeast   197 LKILNKKLLFKLNETNHVLTERDILTTTRSDWLVKLLYAFQDPESLYLAMEFVPGGDFRTLLINT 261

Human   188 RYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMV 252
            |.   |.....:||::|:..||:::|.:||.|||:||||.|:|.||||||.|||.||...||:.:
Yeast   262 RI---LKSGHARFYISEMFCAVNALHELGYTHRDLKPENFLIDATGHIKLTDFGLAAGTVSNERI 323

Human   253 -----------NAKLP----------------------------IGTPDYMAPEVLTVMNGDGKG 278
                       |.:.|                            :|:|||||.|||     :|| 
Yeast   324 ESMKIRLEEVKNLEFPAFTERSIEDRRKIYHNMRKTEINYANSMVGSPDYMALEVL-----EGK- 382

Human   279 TYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFP--DDPKV--SSDFLDLIQ 339
            .|....|:||:|.:.:|.:.|.:||:..::..|:.|:..:::.|:.|  :|.:.  |....|||.
Yeast   383 KYDFTVDYWSLGCMLFESLVGYTPFSGSSTNETYENLRYWKKTLRRPRTEDRRAAFSDRTWDLIT 447

Human   340 SLLCGQKERLK-FEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDEPEKNSWVSSSPCQ 403
            .|:.....|:: ||.:....:|::|::..:|.|.|||:|.|..:.|...||:             
Yeast   448 RLIADPINRVRSFEQVRKMSYFAEINFETLRTSSPPFIPQLDDETDAGYFDD------------- 499

Human   404 LSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLL 452
                 |:.||      ..:|...:..|...:.:.:|.    |:::.||:
Yeast   500 -----FTNEE------DMAKYADVFKRQNKLSAMVDD----SAVDSKLV 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CITXP_011536085.1 STKc_CRIK 95..422 CDD:270752 119/372 (32%)
S_TKc 97..360 CDD:214567 102/308 (33%)
Smc 474..1335 CDD:224117
C1 1405..1453 CDD:237996
PH 1486..1605 CDD:278594
CNH 1650..1946 CDD:214481
DBF20NP_015436.1 STKc_Sid2p_like 157..539 CDD:270751 127/414 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.