Protein Alignment KATNA1 and CG1271

DIOPT Version :10

• Sequence 1: NP_008975.1
• Gene: KATNA1 / 11104
• HGNCID: 6216
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_647763.1
• Gene: CG1271 / 38364
• FlyBaseID: FBgn0035392
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 209
• Identity: 44/209 - (21%)
• Similarity: 73/209 - (34%)
• Gaps: 79/209 - (37%)

Human   246 LMVGPPGTGKTLLAKAVATECKTTFFNVSSSTL---TSKYRGES-----------EKLVRLLFEM 296
            |...|..|..  :|::| .:....||..:.|.|   .:.||..|           ..:||.|.|.
  Fly   380 LFDSPANTSD--IAQSV-PDTNDVFFMPAFSGLGPPVNDYRSASGFIGLTPSTTKAHMVRALLES 441

Human   297 ARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSEND-------DPSKMVM 354
            ..|.....|             .:.|.|.|:::.   ::::|  ||.|.||       |.|::.:
  Fly   442 IVFRLVQLI-------------EAAEKETSQKLH---MIRVD--GGVSRNDFVCQFLADLSRLRV 488

Human   355 ---------VLAATNFP------W-DIDEALRRRLEKRIYIPLPSAKGREELLRISLRELELADD 403
                     ::.||...      | |:::..|.|...|::.|.|             :|.|
  Fly   489 ERADNAESSIMGATFMAGINLGIWRDVNDLKRFRKVARVFEPRP-------------KEYE---- 536

Human   404 VDLASIAENMEGYS 417
                :||..|:.:|
  Fly   537 ----TIANRMDKWS 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KATNA1	NP_008975.1	Interaction with microtubules	1..185
		Interaction with dynein and NDEL1. /evidence=ECO:0000250	1..75
		Interaction with KATNB1. /evidence=ECO:0000269|PubMed:10751153	1..29
		Kp60-NTD	5..72	CDD:439297
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..185
		RecA-like_KTNA1	210..379	CDD:410930	36/169 (21%)
		AAA_lid_3	403..447	CDD:465537	4/15 (27%)
		Vps4_C	<451..489	CDD:462762
CG1271	NP_647763.1	ASKHA_NBD_FGGY_GK5-like	32..549	CDD:466803	44/209 (21%)