DRSC/TRiP Functional Genomics Resources

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Protein Alignment ADCY5 and CG3216

DIOPT Version :9

Sequence 1:NP_001365188.1 Gene:ADCY5 / 111 HGNCID:236 Length:1286 Species:Homo sapiens
Sequence 2:NP_726013.2 Gene:CG3216 / 37376 FlyBaseID:FBgn0034568 Length:1161 Species:Drosophila melanogaster


Alignment Length:243 Identity:84/243 - (34%)
Similarity:132/243 - (54%) Gaps:35/243 - (14%)


- Green bases have known domain annotations that are detailed below.


Human  1046 QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYV 1110
            |.:.||:..||       ||:.|||:.||...:|    .|.:..:....|.:.|:.|..|:    
  Fly   915 QLSLEKQRTEE-------LLYQILPRPVAQQLMA----GDLVEPEEFSSVTIYFSDIVGFT---- 964

Human  1111 ELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKA 1175
            ||.|.:..::.:..||::.:.||.||.   |..:.|::|||..|:..|||.:...||    |.:.
  Fly   965 ELCARSSPMDVVNFLNDLYSTFDRIIG---FYDVYKVETIGDAYLVVSGLPEPNGDK----HARE 1022

Human  1176 LADFAMKLMDQMKYINEHSFN-------NFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASR 1233
            :|..|:.::..:.     |||       ..|::||::.|.|.|||:|.:.|.|.::|:|||.|||
  Fly  1023 IALMALDILRAVS-----SFNLRHKPEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASR 1082

Human  1234 MDSTGVPDRIQVTTDMYQVL-AANTYQLECRGVVKVKGKGEMMTYFLN 1280
            |:|||.|.:|.|::....:| ...|:|:|.||.|::||||.:.||:||
  Fly  1083 MESTGQPGKIHVSSATKAILDKFGTFQMEQRGDVELKGKGTVTTYWLN 1130

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ADCY5NP_001365188.1 AC_N 1..458 CDD:318454
Guanylate_cyc 460..633 CDD:306677
DUF1053 668..760 CDD:399378
Guanylate_cyc 1087..1281 CDD:306677 70/202 (35%)
CG3216NP_726013.2 PBP1_NPR_like 90..496 CDD:107368
ANF_receptor 107..479 CDD:279440
PKc_like 616..885 CDD:304357
TyrKc 627..877 CDD:197581
HNOBA <882..939 CDD:285003 12/30 (40%)
CYCc 918..1109 CDD:214485 70/217 (32%)
Guanylate_cyc 945..1131 CDD:278633 70/202 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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