Protein Alignment NUP42 and CG18789

DIOPT Version :9

• Sequence 1: NP_001357372.1
• Gene: NUP42 / 11097
• HGNCID: 17010
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_723704.1
• Gene: CG18789 / 317813
• FlyBaseID: FBgn0042127
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 99/519 - (19%)
• Similarity: 153/519 - (29%)
• Gaps: 202/519 - (38%)

Human     1 MAICQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRYSNVIQPSSFSK 65
            |.:|:||.||.||:|.:|.|||
  Fly     1 MVVCRFFQQGSCRYGAKCNNEH------------------------------------------- 22

Human    66 STPWGGSRDQEKPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGIVKDMEVWESS 130
                                                         .|.|:.|:.   |||...:.
  Fly    23 ---------------------------------------------FDVKQYLKA---DMESSLNG 39

Human   131 GQWMFSVYSPVKKKPNISGF-TDISPEELRLEYHNFLTSNNLQSYLNSVQRLINQWRNRVNELKS 194
            ..|..|.|.|.|.|.|...| .|.|.||:|...:.....|..:.:.....|.:.:..|::..:
  Fly    40 KMWPLSAYGPFKDKANFPNFIQDQSFEEVRFMCYEAKRQNQFEQFSQQFNREVLEANNKMKTM-- 102

Human   195 LNISTKVALKCLWKIYTHLSPKIYGPDCGKFIIFLSDVKDGVNQAAPAFGFGSSQAATFMSPGFP 259
            |.:|.:| |:.:.||:.       .|:.|..........:....||||  ..::.|:.|..|...
  Fly   103 LQMSPQV-LEMMIKIHE-------TPEGGTVSAAPQQSSNPFAAAAPA--AANTSASIFGKPTLS 157

Human   260 VNNSSSDNAQNFSFKTNSGFAAASSGSPAG---FGSSPAFGAAASTSSGISTSAPAFGFGKPEVT 321
            ..|... ||.:.:..|||.|....|.:.|.   ||    .||||:.:..:        ||:|:..
  Fly   158 AGNIFG-NATSQASNTNSIFGGTISNANARNSIFG----VGAAATGAQSV--------FGQPQQQ 209

Human   322 SAASFSFKSPAASSF-GSPGFSGLPASLATGPVRAPVAPAFGG-------GSSVAGFGSPGSHSH 378
            ..      .|||.:| |...|:.....:...||.   ...|||       ..|...||...|.:.
  Fly   210 QL------QPAAQAFQGGNIFAQAQVQVQAQPVN---PNPFGGFQQQQQQPQSTGIFGQAASQNM 265

Human   379 TAFSKPSSDTF--GNSSISTSLSASSSIIATDN-------------------------------- 409
            ......:|...  ...:.::.|.|.::..|..|
  Fly   266 GGMFTQASQQLQQQQQAAASGLFAQAAASAFPNQQQMQQQQQMQQQQQMQQQQMHQQQQMQQQQM 330

Human   410 -------------------------------VLFTPRDKLTVEELEQFQSKKFTLGKIPLKPPP 442
                                           .:::..:.|..:|:|.|::.:|..|.:|.||||
  Fly   331 QQQQQQFQMQQQQQMMQQQQQQAQPTNEIQSSVYSRMEDLNEQEIEAFKADQFLPGALPFKPPP 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NUP42	NP_001357372.1	zf_CCCH_4	4..22	CDD:375772	10/17 (59%)
		Nucleoporin_FG2	<238..340	CDD:374260	30/105 (29%)
CG18789	NP_723704.1	ZnF_C3H1	1..22	CDD:214632	11/20 (55%)
		Nucleoporin_FG	145..>204	CDD:290362	18/71 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28W1G
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	72	1.000	Inparanoid score	I5303
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562631at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46527
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4413
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.990