Protein Alignment DNAJB4 and DnaJ-1

DIOPT Version :10

• Sequence 1: NP_008965.2
• Gene: DNAJB4 / 11080
• HGNCID: 14886
• Length: 337
• Species: Homo sapiens
• Sequence 2: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 194/346 - (56%)
• Similarity: 246/346 - (71%)
• Gaps: 24/346 - (6%)

Human     1 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYD 65
            ||||:|.|||:|:.|||::|||||||.|||:||||||||||||:|||:|||||||||.|||:|:|
  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65

Human    66 QFGEEGLKGGAGGTDGQG--GTFRYTFHGDPHATFAAFFGGSNPFEIFF--GRRM---GGGRDSE 123
            .:||:|||||..|.||.|  |.:.|.|||||.||||.|||.|:||..||  |..|   |.|.::.
  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTN 130

Human   124 EM--EIDGDPFSAFGFSMNGYPRDRNSVGPSRLK-QDPPVIHELRVSLEEIYSGCTKRMKISRKR 185
            |:  .|.||...||           |:..|||.: ||||:.|:|.|||||:..||.|:|||||..
  Fly   131 EIFWNIGGDDMFAF-----------NAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISRMA 184

Human   186 LNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNI 250
            ..::| .|: |:|:|.|.:|.|||.|||||||:|||..||..||||||||:||.|..|||:|.::
  Fly   185 TGSNG-PYK-EEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGIDL 247

Human   251 IYTAKISLREALCGCSINVPTLDGRNIPMSVN-DIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEF 314
            .|||:|||::||||..::||||.|..|.::.| :|:||...|||.|.|||.||.|.:||||::.|
  Fly   248 KYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSF 312

Human   315 EVSFPDTISSSSKEVLRKHLP 335
            ::.||||::.|.:..|.:.||
  Fly   313 DIKFPDTLAPSLQNQLSELLP 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB4	NP_008965.2	DnaJ_bact	4..332	CDD:274090	189/338 (56%)
DnaJ-1	NP_523936.2	DnaJ_bact	4..332	CDD:274090	189/340 (56%)