Protein Alignment DNAJB4 and shv

DIOPT Version :10

• Sequence 1: NP_008965.2
• Gene: DNAJB4 / 11080
• HGNCID: 14886
• Length: 337
• Species: Homo sapiens
• Sequence 2: NP_608525.1
• Gene: shv / 33220
• FlyBaseID: FBgn0031256
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 118/377 - (31%)
• Similarity: 176/377 - (46%)
• Gaps: 95/377 - (25%)

Human     2 GKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNK-SPQAEEKFKEVAEAYEVLSDPKKREIYD 65
            |:|:|.||.::|.|:..::|||||:.|.:.|||||| .|.|..||:::..||||||:|.||:.||
  Fly    23 GRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNPDKRKTYD 87

Human    66 QFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGD 130
            :.|||.||  ..|....|        |||   |::|||.       ||...||         ||.
  Fly    88 RCGEECLK--KEGMMDHG--------GDP---FSSFFGD-------FGFHFGG---------DGQ 123

Human   131 PFSAFGFSMNGYPRDRNSVGPSRLKQDPP----VIHELRVSLEEIYSG----------------- 174
                                    :||.|    ::.:|.|||||:|||
  Fly   124 ------------------------QQDAPRGADIVMDLYVSLEELYSGNFVEIVRNKPVTKPASG 164

Human   175 ---CTKRMKISRKRLNADGR---------------SYRSEDKILTIEIKKGWKEGTKITFPREGD 221
               |..|.::..:.| ..||               ...:|::.|.||:::|..:|.:..|..||:
  Fly   165 TRKCNCRQEMVTRNL-GPGRFQMIQQTVCDECPNVKLVNEERTLEIEVEQGMVDGQETRFVAEGE 228

Human   222 ETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVK 286
            ...:..|.|::..::...||:|.|...::.....|||::||.|.|:.:..|||..:|::...:..
  Fly   229 PHIDGEPGDLIVRVQQMPHPRFLRKNDDLYTNVTISLQDALVGFSMEIKHLDGHLVPVTREKVTW 293

Human   287 PGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFP-DTISSSSKEVLRKHLPAS 337
            ||.|.|..|.|:|..:|.:..|:|.|.|:|.|| ..::...||.|:|.|..|
  Fly   294 PGARIRKKGEGMPNFENNNLTGNLYITFDVEFPKKDLTEEDKEALKKILDQS 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB4	NP_008965.2	DnaJ_bact	4..332	CDD:274090	114/368 (31%)
shv	NP_608525.1	DnaJ_bact	25..345	CDD:274090	116/373 (31%)