Protein Alignment TPPP and ringer

DIOPT Version :10

• Sequence 1: XP_016864482.1
• Gene: TPPP / 11076
• HGNCID: 24164
• Length: 286
• Species: Homo sapiens
• Sequence 2: NP_648881.1
• Gene: ringer / 39813
• FlyBaseID: FBgn0266417
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 203
• Identity: 78/203 - (38%)
• Similarity: 115/203 - (56%)
• Gaps: 19/203 - (9%)

Human    77 AANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDARATGREMHGK 141
            |||.:|..:|..........:|:||.|         |::| ..:.|:.|:..||:::.|:.:...
  Fly     6 AANGSPSPAPTPEVPATELAQLALEDE---------PKVS-FSDQFKAFSKFGDSKSDGKLITLS 60

Human   142 NWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVRE 206
            ...|..|..:||| :.:|.||..|.|.|.|...   |:...:.:.|::|||.: |.:.||  :::
  Fly    61 QSDKWMKQAKVID-KKITTTDTGIHFKKFKAMK---ISLSDYNKFLDDLAKTK-KVELSE--IKQ 118

Human   207 VHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSG 271
              :|....||.:..|:...::..|.|||||:|:|||||||||.||||||.|||.::||.||||||
  Fly   119 --KLASCGAPGVVSVSAGKAAAAVDRLTDTSKYTGSHKERFDASGKGKGIAGRRNVVDGSGYVSG 181

Human   272 YKHAGTYD 279
            |:|..|||
  Fly   182 YQHKDTYD 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPPP	XP_016864482.1	p25-alpha	119..274	CDD:461670	63/154 (41%)
ringer	NP_648881.1	p25-alpha	39..184	CDD:461670	63/153 (41%)