Protein Alignment TPPP and Tppp

DIOPT Version :10

• Sequence 1: XP_016864482.1
• Gene: TPPP / 11076
• HGNCID: 24164
• Length: 286
• Species: Homo sapiens
• Sequence 2: NP_001101931.1
• Gene: Tppp / 361466
• RGDID: 1310121
• Length: 218
• Species: Rattus norvegicus
• Alignment Length: 220
• Identity: 202/220 - (91%)
• Similarity: 211/220 - (95%)
• Gaps: 3/220 - (1%)

Human    68 MAD-KAKPAKAANRTPPKSPGDPSKDRAAKRLSLESEGAGEGAAASPELSALEEAFRRFAVHGDA 131
            ||| ||||.||||:|||||||||:|  ||||||||||||.|||||:||||||||||||||||||.
  Rat     1 MADSKAKPTKAANKTPPKSPGDPAK--AAKRLSLESEGANEGAAAAPELSALEEAFRRFAVHGDT 63

Human   132 RATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFK 196
            ||||:||||||||||||||.||||:||||||||||||||||||||||||||||||||||||||||
  Rat    64 RATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFK 128

Human   197 DKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVD 261
            |||||||||||||||||:||:|||||||:|||||||||||:|||||||||||.||||||||||||
  Rat   129 DKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVD 193

Human   262 LVDESGYVSGYKHAGTYDQKVQGGK 286
            ||||||||.||||||||||||||||
  Rat   194 LVDESGYVPGYKHAGTYDQKVQGGK 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPPP	XP_016864482.1	p25-alpha	119..274	CDD:461670	144/154 (94%)
Tppp	NP_001101931.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		38/45 (84%)
		Mediates interaction with LIMK1. /evidence=ECO:0000250|UniProtKB:O94811	2..115		102/114 (89%)
		p25-alpha	51..206	CDD:461670	144/154 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..192		24/26 (92%)