Protein Alignment TPPP and tppp-1

DIOPT Version :10

• Sequence 1: XP_016864482.1
• Gene: TPPP / 11076
• HGNCID: 24164
• Length: 286
• Species: Homo sapiens
• Sequence 2: NP_491219.1
• Gene: tppp-1 / 171948
• WormBaseID: WBGene00016321
• Length: 180
• Species: Caenorhabditis elegans
• Alignment Length: 166
• Identity: 66/166 - (39%)
• Similarity: 97/166 - (58%)
• Gaps: 13/166 - (7%)

Human   120 EAFRRFAVHGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSCRTITFEQFQ 184
            :||.:|..     ||..||.|||:.|..||..|:|.:.:|.|...|.|||:.|.. :..||::.:
 Worm    19 DAFTKFGA-----ATATEMTGKNFDKWLKDAGVLDNKAITGTMTGIAFSKVTGPK-KKATFDETK 77

Human   185 EALEELAKKRFKDKSSE-----EAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHK 244
            :.|..:|:.|.:.....     :|:.|  :|.:.:||.:.|..||.::...|||||.||:||:||
 Worm    78 KVLAFVAEDRARQSKKPIQDELDAITE--KLAKLEAPSVGGAAKANAAGVYSRLTDHTKYTGAHK 140

Human   245 ERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQ 280
            ||||..||||||:||.|..:.:|||..||:..:||:
 Worm   141 ERFDAEGKGKGKSGRADTTENTGYVGAYKNKDSYDK 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TPPP	XP_016864482.1	p25-alpha	119..274	CDD:461670	63/158 (40%)
tppp-1	NP_491219.1	p25-alpha	15..170	CDD:461670	63/158 (40%)