DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNRNP35 and Rox8

DIOPT Version :9

Sequence 1:	NP_851030.1	Gene:	SNRNP35 / 11066	HGNCID:	30852	Length:	251	Species:	Homo sapiens
Sequence 2:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	127	Identity:	37/127 - (29%)
Similarity:	58/127 - (45%)	Gaps:	21/127 - (16%)

- Green bases have known domain annotations that are detailed below.

Human    58 LFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVI 122
            :||..|:.:.:.:.|:|.|:.:|:|...|:|||..|..||||||:.:.::.....|.:..:|..|
  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWI 161

Human   123 DQHEIFVDYELERTLKGWIPRRL------------GGGLGGKKESGQLRFGGRDRPFRKPIN 172
            ....|       ||  .|..|:|            |||:||...:|....|.:...|.:..|
  Fly   162 GSRSI-------RT--NWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYN 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNRNP35	NP_851030.1	RRM_snRNP35	53..142	CDD:240683	26/83 (31%)
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	37/127 (29%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799	25/81 (31%)
		RRM3_TIA1_like	221..294	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810