DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNRNP35 and rnp-7

DIOPT Version :9

Sequence 1:	NP_851030.1	Gene:	SNRNP35 / 11066	HGNCID:	30852	Length:	251	Species:	Homo sapiens
Sequence 2:	NP_498565.2	Gene:	rnp-7 / 176002	WormBaseID:	WBGene00004390	Length:	332	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	71/200 - (35%)
Similarity:	95/200 - (47%)	Gaps:	51/200 - (25%)

- Green bases have known domain annotations that are detailed below.

Human    53 DPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVIKAYRDA 117
            ||..||||.|:|.:|.|.||:..|..||.|::|.:|.| ..|..:|||||||.::..:..||:.|
Worm   101 DPYRTLFVGRINYETSESKLRREFEAYGKIKKLTMVHD-EAGKPRGYAFIEYSDKAEMHTAYKKA 164

Human   118 DGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLR-----------FGGRDRPFRKPI 171
            ||:.:|...:.||||..||.|.|:|||||||.|..:::.:.:           |||
Worm   165 DGIKVDGKRLVVDYERGRTQKTWLPRRLGGGKGDTRKTREAKSVIEEREIASGFGG--------- 220

Human   172 NLPVVKNDLYREGKRER-RERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERD 235
                        |..:| ||||.||:|..||......:||.|.                 |....
Worm   221 ------------GYEDRDRERSGSRDRRQDSYRNGGGNDRDRR-----------------ESSGG 256

Human   236 FRDDR 240
            |||:|
Worm   257 FRDNR 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNRNP35	NP_851030.1	RRM_snRNP35	53..142	CDD:240683	41/88 (47%)
rnp-7	NP_498565.2	U1snRNP70_N	4..94	CDD:371969
rnp-7	NP_498565.2	RRM_snRNP70	103..192	CDD:240682	41/89 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1430110at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820