Protein Alignment UPK1A and lbm

DIOPT Version :10

• Sequence 1: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 42/187 - (22%)
• Similarity: 68/187 - (36%)
• Gaps: 59/187 - (31%)

Human    67 IAIFCGFSFFMV-ASFGVGAALCRRRSMVL--TYLVLMLIVYIFECASCITSYTHRDYMVSNPSL 128
            ||.:...|..:| |..|:.||:  |.|:||  |..|.:||:.|.:
  Fly    43 IAAYIACSLILVFALLGIFAAI--RESVVLTATSAVFLLILAILQ-------------------- 85

Human   129 ITKQMLTFYSADTDQGQELTRL-W-----DRVMIEQECCGTSGPMDWVNFTSAFRAATPEVVFPW 187
            |....|..:..|...|:::..: |     |.:..:.||||.|...|:::.:...
  Fly    86 IVSTCLFLHEFDVKSGRDMVEVAWQANNMDSLQQKHECCGQSSAQDYIHLSLLI----------- 139

Human   188 PPLCCRRTGNFIPLNEEGCRLGHMDYLFTKGCFEHIGHAIDSYTWGISWFGFAILMW 244
            ||.|      :..|.:.      .|:|:..||.|.:....:|     ....|.|:.|
  Fly   140 PPSC------YADLQQT------PDHLYLDGCIEKVQSFYES-----DKLRFIIVSW 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	26/104 (25%)
		uroplakin_I_like_LEL	113..231	CDD:239409	22/123 (18%)
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	40/183 (22%)
		tetraspanin_LEL	<109..169	CDD:239401	17/82 (21%)