| Sequence 1: | NP_006862.2 | Gene: | RIPK3 / 11035 | HGNCID: | 10021 | Length: | 518 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_064339.2 | Gene: | Ripk3 / 56532 | MGIID: | 2154952 | Length: | 486 | Species: | Mus musculus |
| Alignment Length: | 497 | Identity: | 299/497 - (60%) |
|---|---|---|---|
| Similarity: | 347/497 - (69%) | Gaps: | 23/497 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MSCVKLWPSGAPA-PLVSIEELENQELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAM 64
Human 65 ASLDNEFVLRLEGVIEKVNWDQDPKPALVTKFMENGSLSGLLQSQCPRPWPLLCRLLKEVVLGMF 129
Human 130 YLHDQNPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSGTGSG----EPGGTLGYLAPEL 190
Human 191 FVNVNRKASTASDVYSFGILMWAVLAGREVELPTEPSLVYEAVCNRQNRPSLAELPQAGPETPGL 255
Human 256 EGLKELMQLCWSSEPKDRPSFQECLPKTDEVFQMVENNMNAAVSTVKDFLSQLRSSNRRFSIPES 320
Human 321 GQGGTEMDGFRRTIENQHSRNDVMVSEWLNKLNLEEPPSSVPKKCPSLTKRSRAQEEQVPQAWTA 385
Human 386 GTSSDSMAQPPQTPETSTFRNQMPSPTSTGTPSPGPRGNQGAERQGMNWSCRTPEPNPVTGRPLV 450
Human 451 NIYNCSGVQVGD-NNYLTMQQTTALPT--WGLAPSGKGRGLQ 489 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RIPK3 | NP_006862.2 | S_TKc | 22..280 | CDD:214567 | 185/261 (71%) |
| PKc_like | 27..280 | CDD:304357 | 184/256 (72%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 355..443 | 40/87 (46%) | |||
| RHIM | 419..468 | CDD:289491 | 23/49 (47%) | ||
| RIP homotypic interaction motif (RHIM). /evidence=ECO:0000269|PubMed:29681455 | 450..466 | 7/16 (44%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 476..518 | 6/16 (38%) | |||
| Ripk3 | NP_064339.2 | Pkinase | 24..284 | CDD:278497 | 185/259 (71%) |
| PKc_like | 28..284 | CDD:304357 | 184/255 (72%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 312..333 | 11/20 (55%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 349..388 | 19/42 (45%) | |||
| RHIM | 410..457 | CDD:289491 | 23/47 (49%) | ||
| RIP homotypic interaction motif (RHIM). /evidence=ECO:0000269|PubMed:18442983 | 440..461 | 7/20 (35%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 462..486 | 9/21 (43%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83973640 | |
| Domainoid | 1 | 1.000 | 368 | 1.000 | Domainoid score | I12653 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0192 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H31410 | |
| Inparanoid | 1 | 1.050 | 540 | 1.000 | Inparanoid score | I11522 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S5963 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG34949 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0007085 | |
| OrthoInspector | 1 | 1.000 | - | - | oto118642 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_121923 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23257 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X6895 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.210 | |||||