Protein Alignment DSTN and COF1

DIOPT Version :10

• Sequence 1: NP_006861.1
• Gene: DSTN / 11034
• HGNCID: 15750
• Length: 165
• Species: Homo sapiens
• Sequence 2: NP_013050.1
• Gene: COF1 / 850676
• SGDID: S000003973
• Length: 143
• Species: Saccharomyces cerevisiae
• Alignment Length: 153
• Identity: 53/153 - (34%)
• Similarity: 86/153 - (56%)
• Gaps: 23/153 - (15%)

Human     3 SGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDP 67
            |||.||||....|.|:|         :.|:.|.::|.|:..|..|:|:|           |.|||
Yeast     4 SGVAVADESLTAFNDLK---------LGKKYKFILFGLNDAKTEIVVKE-----------TSTDP 48

Human    68 -FKHFVGMLPEKDCRYALYDASFET--KESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQ 129
             :..|:..|||.||.||:||..:|.  .|.::.:::||.|:|:.||::|||:|||||||:::...
Yeast    49 SYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALN 113

Human   130 GIKHECQANGPEDLNRACIAEKL 152
            |:..:.|.....:::...:.|::
Yeast   114 GVSTDVQGTDFSEVSYDSVLERV 136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DSTN	NP_006861.1	ADF_cofilin_like	3..152	CDD:200442	53/151 (35%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		1/3 (33%)
COF1	NP_013050.1	ADF_cofilin_like	4..136	CDD:200442	53/151 (35%)