Protein Alignment DSTN and F53E2.2

DIOPT Version :10

• Sequence 1: NP_006861.1
• Gene: DSTN / 11034
• HGNCID: 15750
• Length: 165
• Species: Homo sapiens
• Sequence 2: NP_503425.2
• Gene: F53E2.2 / 41657006
• WormBaseID: WBGene00302980
• Length: 165
• Species: Caenorhabditis elegans
• Alignment Length: 178
• Identity: 51/178 - (28%)
• Similarity: 81/178 - (45%)
• Gaps: 40/178 - (22%)

Human     1 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTIT 65
            |:|||.|..:|...|..:        .|.:|..:.:||.:..:|  :|||..  :....:|:|..
 Worm     1 MSSGVMVDPDVQTSFQKL--------SEGRKEYRYIIFKIDENK--VIVEAA--VTQDQLGITGD 53

Human    66 D-------PFKHFVGMLPEK-----DCRYALYDASFETKE-----SRKEELMFFLWAPELAPLKS 113
            |       .|..||..:..:     |||||::|..|....     |:.::::|....|:.|.:|.
 Worm    54 DYDDSSKAAFDKFVEDVKSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKK 118

Human   114 KMIYASSKDAIKK--------KFQGIKHECQANGPEDLNRACIAEKLG 153
            ||:||||..|||.        :|| :..|.:.:..|.||:  :.||.|
 Worm   119 KMVYASSAAAIKTSLGTGKILQFQ-VSDESEMSHKELLNK--LGEKYG 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DSTN	NP_006861.1	ADF_cofilin_like	3..152	CDD:200442	48/173 (28%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		1/3 (33%)
F53E2.2	NP_503425.2	ADF_cofilin_like	3..158	CDD:200442	47/169 (28%)