Protein Alignment DSTN and tsr

DIOPT Version :10

• Sequence 1: NP_006861.1
• Gene: DSTN / 11034
• HGNCID: 15750
• Length: 165
• Species: Homo sapiens
• Sequence 2: NP_477034.1
• Gene: tsr / 37841
• FlyBaseID: FBgn0011726
• Length: 148
• Species: Drosophila melanogaster
• Alignment Length: 162
• Identity: 61/162 - (37%)
• Similarity: 82/162 - (50%)
• Gaps: 30/162 - (18%)

Human     1 MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKK--AVIFCLSADKKCIIVEEGKEILVGDVGVT 63
            |||||.|:| ||:..|          |||||.||  .|||.: .|:|.|.||     .|.|....
  Fly     1 MASGVTVSD-VCKTTY----------EEIKKDKKHRYVIFYI-RDEKQIDVE-----TVADRNAE 48

Human    64 ITDPFKHFVGMLPEKDCRYALYDASFE-------TKESRKEELMFFL-WAPELAPLKSKMIYASS 120
            . |.|...:......:|||.|:|  ||       |.||.|::.:|.: |.|:.|.:|.||:|:||
  Fly    49 Y-DQFLEDIQKCGPGECRYGLFD--FEYMHQCQGTSESSKKQKLFLMSWCPDTAKVKKKMLYSSS 110

Human   121 KDAIKKKFQGIKHECQANGPEDLNRACIAEKL 152
            .||:||...|::...||....:.:|..:.|||
  Fly   111 FDALKKSLVGVQKYIQATDLSEASREAVEEKL 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DSTN	NP_006861.1	ADF_cofilin_like	3..152	CDD:200442	57/158 (36%)
		Nuclear localization signal. /evidence=ECO:0000255	30..34		2/3 (67%)
tsr	NP_477034.1	ADF_cofilin_like	3..142	CDD:200442	57/158 (36%)