DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMED1 and CHOp24

DIOPT Version :9

Sequence 1:NP_006849.1 Gene:TMED1 / 11018 HGNCID:17291 Length:227 Species:Homo sapiens
Sequence 2:NP_001284862.1 Gene:CHOp24 / 31382 FlyBaseID:FBgn0029709 Length:208 Species:Drosophila melanogaster


Alignment Length:196 Identity:55/196 - (28%)
Similarity:91/196 - (46%) Gaps:16/196 - (8%)


- Green bases have known domain annotations that are detailed below.


Human    34 FTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPT 98
            |...:.|..::||:::..........::||.|..||||..:..|...::....:::.|.:|....
  Fly    25 FIVSVDAHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAP 89

Human    99 EAGDYKLCFDNSFSTISEKLVFFEL-IFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMR 162
            ..|.|.:||:|..|:::.|||.|.: :.|:.|......|      .||:...|:||:...:....
  Fly    90 AKGTYTVCFNNERSSMTPKLVMFSIDVGDAPQRAPGAPG------EEEVGHTKLEDMIRELSGTL 148

Human   163 TRLERSIQMLTLLRAFEARD---RNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRP 224
            |.::...:.:      ..||   |::.|....||..||.....||:|:.|.||..|||||:.||.
  Fly   149 TSVKHEQEYM------HVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRV 207

Human   225 V 225
            |
  Fly   208 V 208

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
TMED1NP_006849.1 EMP24_GP25L 33..220 CDD:395878 51/189 (27%)
COPI vesicle coat-binding. /evidence=ECO:0000255 218..227 5/8 (63%)