Protein Alignment KLK11 and CG18735

DIOPT Version :10

• Sequence 1: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Sequence 2: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Alignment Length: 310
• Identity: 94/310 - (30%)
• Similarity: 142/310 - (45%)
• Gaps: 51/310 - (16%)

Human     9 DWKSSGRGLTAAKEPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFE 73
            ||..|   :...:.|...|||.:..      ....:.|.:....||:.|.|.:.|..||...|..
  Fly    47 DWIQS---ILGPEVPAEWSSPAKRE------CAECSCGNINTRHRIVGGQETEVHEYPWMIMLMW 102

Human    74 KTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYI-VHLGQHNLQKE 137
            .....|||:|:..::.||||||:.                      ....|.| |.|.:||.|..
  Fly   103 FGNFYCGASLVNDQYALTAAHCVN----------------------GFYHRLITVRLLEHNRQDS 145

Human   138 EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT-AGTSCLI 201
            ......|..:....||.::    .::..:||.|::...||.:...:.|:.:.:.... ||.:.::
  Fly   146 HVKIVDRRVSRVLIHPKYS----TRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVV 206

Human   202 SGWGSTS--SPQLRLPHTLRCANITIIEHQKCENAYPG--NITDTMVCAS-VQEGGKDSCQGDSG 261
            :|||:.|  .|   :..||:...:.|:..::|.|:..|  .|||.|:||. |::|||||||||||
  Fly   207 TGWGALSEGGP---ISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSG 268

Human   262 GPLVCNQS-----LQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKN 306
            ||:....|     |.||:|||:. ||....|||||:|..:.|||.|..::
  Fly   269 GPMHVLGSGDAYQLAGIVSWGEG-CAKPNAPGVYTRVGSFNDWIAENTRD 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	83/258 (32%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	84/260 (32%)